methyl 3-<1-(4-chlorobenzyl)-7-hydroxy-1,4-dihydrothiepino<2,3,4-c,d>indol-2-yl>-2,2-dimethylpropanoate

Base Information

Chemical Name:methyl 3-<1-(4-chlorobenzyl)-7-hydroxy-1,4-dihydrothiepino<2,3,4-c,d>indol-2-yl>-2,2-dimethylpropanoate
CAS No.:147937-20-0
Molecular Formula:C₂₄H₂₄ClNO₃S
Molecular Weight:441.978
Hs Code.:

Synonyms:methyl 3-<1-(4-chlorobenzyl)-7-hydroxy-1,4-dihydrothiepino<2,3,4-c,d>indol-2-yl>-2,2-dimethylpropanoate

Suppliers and Price of methyl 3-<1-(4-chlorobenzyl)-7-hydroxy-1,4-dihydrothiepino<2,3,4-c,d>indol-2-yl>-2,2-dimethylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 3-<1-(4-chlorobenzyl)-7-hydroxy-1,4-dihydrothiepino<2,3,4-c,d>indol-2-yl>-2,2-dimethylpropanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 3-<1-(4-chlorobenzyl)-7-hydroxy-1,4-dihydrothiepino<2,3,4-c,d>indol-2-yl>-2,2-dimethylpropanoate

There total 6 articles about methyl 3-<1-(4-chlorobenzyl)-7-hydroxy-1,4-dihydrothiepino<2,3,4-c,d>indol-2-yl>-2,2-dimethylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 147937-19-7
methyl 3-<1-(4-chlorobenzyl)-3-<(2-formylethyl)thio>-5-hydroxyindol-2-yl>-2,2-dimethylpropanoate

: 147937-20-0
methyl 3-<1-(4-chlorobenzyl)-7-hydroxy-1,4-dihydrothiepino<2,3,4-c,d>indol-2-yl>-2,2-dimethylpropanoate

Guidance literature:: With hydrogenchloride; In diethyl ether; for 0.5h; Yield given;
DOI:10.1021/jm00071a008

Reference yield:

: 20955-94-6
1-[(4-chlorophenyl)methyl]-1-(4-methoxyphenyl)-hydrazine hydrochloride

: 147937-20-0
methyl 3-<1-(4-chlorobenzyl)-7-hydroxy-1,4-dihydrothiepino<2,3,4-c,d>indol-2-yl>-2,2-dimethylpropanoate

Guidance literature:: Multi-step reaction with 5 steps

1: 68 percent / NaOAc, glacial AcOH / toluene / 72 h / Ambient temperature

2: ethanethiol, AlCl₃ / CH₂Cl₂ / 0.67 h / 25 °C

3: diethyl ether

4: dimethylformamide / 1 h / 0 °C

5: HCl gas / diethyl ether / 0.5 h

With hydrogenchloride; aluminium trichloride; sodium acetate; acetic acid; ethanethiol; In diethyl ether; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm00071a008

Reference yield:

: methyl 5-(t-butylthio)-2,2-dimethyl-4-oxopentanoate

: 147937-20-0
methyl 3-<1-(4-chlorobenzyl)-7-hydroxy-1,4-dihydrothiepino<2,3,4-c,d>indol-2-yl>-2,2-dimethylpropanoate

Guidance literature:: Multi-step reaction with 5 steps

1: 68 percent / NaOAc, glacial AcOH / toluene / 72 h / Ambient temperature

2: ethanethiol, AlCl₃ / CH₂Cl₂ / 0.67 h / 25 °C

3: diethyl ether

4: dimethylformamide / 1 h / 0 °C

5: HCl gas / diethyl ether / 0.5 h

With hydrogenchloride; aluminium trichloride; sodium acetate; acetic acid; ethanethiol; In diethyl ether; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm00071a008