20-Hydroxyecdysone

Base Information

Chemical Name:20-Hydroxyecdysone
CAS No.:5289-74-7
Molecular Formula:C27H44O7
Molecular Weight:480.642
Hs Code.:29372900
European Community (EC) Number:811-097-1
UNII:779A7KPL0Y
DSSTox Substance ID:DTXSID5040388
Nikkaji Number:J13.425B
Wikipedia:20-Hydroxyecdysone
Wikidata:Q423338
Metabolomics Workbench ID:34497
ChEMBL ID:CHEMBL224128
Mol file:5289-74-7.mol

Synonyms:20 Hydroxyecdysone;20-Hydroxyecdysone;Beta Ecdysone;Beta-Ecdysone;Crustecdysone;Ecdysterone

Suppliers and Price of 20-Hydroxyecdysone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Beta-Ecdysterone
20mg
$ 276.00

TRC
(+)-20-Hydroxyecdysone
1g
$ 80.00

Sigma-Aldrich
20-Hydroxyecdysone ≥93% (HPLC), powder
5mg
$ 164.00

Sigma-Aldrich
20-Hydroxyecdysone ≥93% (HPLC), powder
10mg
$ 299.00

Sigma-Aldrich
20-Hydroxyecdysone ≥93% (HPLC), powder
25mg
$ 648.00

Matrix Scientific
2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one
5g
$ 380.00

Matrix Scientific
2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one
0.500g
$ 100.00

Matrix Scientific
2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one
1g
$ 120.00

JR MediChem
20-Hydroxyecdysone(NewProduct) 98%
100mg
$ 108.00

DC Chemicals
Hydroxyecdysone >98%,StandardReferencesGrade
20 mg
$ 280.00

Total 215 raw suppliers

Chemical Property of 20-Hydroxyecdysone

Chemical Property:

Appearance/Colour:white powder
Vapor Pressure:8.7E-23mmHg at 25°C
Melting Point:242-244 °C
Refractive Index:1.596
Boiling Point:702.1 °C at 760 mmHg
PKA:14.13±0.70(Predicted)
Flash Point:392.4 °C
PSA：138.45000
Density:1.28 g/cm³
LogP:1.85400
Storage Temp.:2-8°C
Solubility.:alcohol: soluble
XLogP3:0.5
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:480.30870374
Heavy Atom Count:34
Complexity:869

Purity/Quality:

Assay99%, ^*data from raw suppliers

Beta-Ecdysterone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 22-24/25-36-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC12CCC3C(=CC(=O)C4C3(CC(C(C4)O)O)C)C1(CCC2C(C)(C(CCC(C)(C)O)O)O)O
Isomeric SMILES:C[C@]12CC[C@H]3C(=CC(=O)[C@H]4[C@@]3(C[C@@H]([C@@H](C4)O)O)C)[C@@]1(CC[C@@H]2[C@](C)([C@@H](CCC(C)(C)O)O)O)O
Recent ClinicalTrials:Testing the Efficacy and Safety of BIO101 for the Prevention of Respiratory Deterioration in COVID-19 Patients
Recent EU Clinical Trials:Adaptive design phase 2 to 3, randomized, double- blind, multicenter, to evaluate the safety, efficacy, pharmacokinetics and pharmacodynamics of BIO101 in the prevention of the respiratory deterioration in hospitalized patients with COVID-19 pneumonia (severe stage)
Uses insect molting hormone 20-Hydroxyecdysone has been used:in Leibovitz′s dissecting medium for culturing sorting zone and neuropil-associated glia and antennal lobes of Manduca sextain Schneider′s medium to reproduce ex-vivo imaginal disc eversionas a supplement in Mcl8 medium for culturing Drosophila wing imaginal discs

Technology Process of 20-Hydroxyecdysone

There total 51 articles about 20-Hydroxyecdysone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%