(2R,3S,5S)-N-benzyloxycarbonyl-3-benzyloxy-2-benzyloxymethyl-5-hydroxymethylpyrrolidine

Base Information

• Chemical Name: (2R,3S,5S)-N-benzyloxycarbonyl-3-benzyloxy-2-benzyloxymethyl-5-hydroxymethylpyrrolidine
• CAS No.: 914649-47-1
• Molecular Formula: C₂₈H₃₁NO₅
• Molecular Weight: 461.558

Synonyms:(2R,3S,5S)-N-benzyloxycarbonyl-3-benzyloxy-2-benzyloxymethyl-5-hydroxymethylpyrrolidine

Chemical Property of (2R,3S,5S)-N-benzyloxycarbonyl-3-benzyloxy-2-benzyloxymethyl-5-hydroxymethylpyrrolidine

Chemical Property:

Purity/Quality:

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Technology Process of (2R,3S,5S)-N-benzyloxycarbonyl-3-benzyloxy-2-benzyloxymethyl-5-hydroxymethylpyrrolidine

There total 1 articles about (2R,3S,5S)-N-benzyloxycarbonyl-3-benzyloxy-2-benzyloxymethyl-5-hydroxymethylpyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C20H25NO3 + benzyl chloroformate (501-53-1,94274-21-2) → (2R,3S,5S)-N-benzyloxycarbonyl-3-benzyloxy-2-benzyloxymethyl-5-hydroxymethylpyrrolidine (914649-47-1)

Guidance literature:

With sodium hydrogencarbonate; sodium carbonate; In water; at 0 - 20 ℃;

DOI:10.1002/chem.200600202

Reference yield:

(2R,3S,5S)-N-benzyloxycarbonyl-3-benzyloxy-2-benzyloxymethyl-5-hydroxymethylpyrrolidine (914649-47-1) → C28H29NO6 (914649-48-2)

Guidance literature:

With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium hydrogencarbonate; potassium bromide; In acetone; at 0 ℃; for 2h;

DOI:10.1002/chem.200600202

upstream raw materials:

benzyl chloroformate

Downstream raw materials:

C₂₈H₂₉NO₆

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