3-(2'-hydroxyethyl)-4-methoxy-N-methyl-N-benzylphenylethanolamine

Base Information

Chemical Name:3-(2'-hydroxyethyl)-4-methoxy-N-methyl-N-benzylphenylethanolamine
CAS No.:79146-25-1
Molecular Formula:C₁₉H₂₅NO₃
Molecular Weight:315.412
Hs Code.:

Synonyms:3-(2'-hydroxyethyl)-4-methoxy-N-methyl-N-benzylphenylethanolamine

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Chemical Property of 3-(2'-hydroxyethyl)-4-methoxy-N-methyl-N-benzylphenylethanolamine

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Technology Process of 3-(2'-hydroxyethyl)-4-methoxy-N-methyl-N-benzylphenylethanolamine

There total 1 articles about 3-(2'-hydroxyethyl)-4-methoxy-N-methyl-N-benzylphenylethanolamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 79146-30-8
3-(2'-hydroxyethyl)-4-methoxy-δ-(N-methyl-N-benzylamino)acetophenone oxalate

: 79146-25-1
3-(2'-hydroxyethyl)-4-methoxy-N-methyl-N-benzylphenylethanolamine

Guidance literature:: With sodium hydroxide; sodium tetrahydroborate; In methanol; for 3h; Ambient temperature;
DOI:10.1021/jm00143a002

Reference yield:

: 79146-25-1
3-(2'-hydroxyethyl)-4-methoxy-N-methyl-N-benzylphenylethanolamine

: 79146-22-8
Acetic acid 2-[2-methoxy-5-(2-methylamino-ethyl)-phenyl]-ethyl ester

Guidance literature:: With perchloric acid; hydrogen; palladium on activated charcoal; In acetic acid; for 22h; under 2068.6 Torr; Ambient temperature;
DOI:10.1021/jm00143a002

Reference yield:

: 79146-25-1
3-(2'-hydroxyethyl)-4-methoxy-N-methyl-N-benzylphenylethanolamine

: 79146-23-9
3-(2'-hydroxyethyl)-4-methoxy-N-methylphenethylamine

Guidance literature:: Multi-step reaction with 2 steps

1: aq. HClO₄, H₂ / 10percent Pd/C / acetic acid / 22 h / 2068.6 Torr / Ambient temperature

2: aq. NaOH / methanol / 4 h / Heating

With sodium hydroxide; perchloric acid; hydrogen; palladium on activated charcoal; In methanol; acetic acid;
DOI:10.1021/jm00143a002