ethyl 4-(9,10-dioxo-9,10-dihydroanthracen-1-yl)-4-oxo-2-(2-(p-tolylcarbamothioyl)hydrazono)butanoate

Base Information

• Chemical Name: ethyl 4-(9,10-dioxo-9,10-dihydroanthracen-1-yl)-4-oxo-2-(2-(p-tolylcarbamothioyl)hydrazono)butanoate
• CAS No.: 1444103-02-9
• Molecular Formula: C₂₈H₂₃N₃O₅S
• Molecular Weight: 513.574
• Mol file: 1444103-02-9.mol

Synonyms:ethyl 4-(9,10-dioxo-9,10-dihydroanthracen-1-yl)-4-oxo-2-(2-(p-tolylcarbamothioyl)hydrazono)butanoate

Chemical Property of ethyl 4-(9,10-dioxo-9,10-dihydroanthracen-1-yl)-4-oxo-2-(2-(p-tolylcarbamothioyl)hydrazono)butanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 4-(9,10-dioxo-9,10-dihydroanthracen-1-yl)-4-oxo-2-(2-(p-tolylcarbamothioyl)hydrazono)butanoate

There total 3 articles about ethyl 4-(9,10-dioxo-9,10-dihydroanthracen-1-yl)-4-oxo-2-(2-(p-tolylcarbamothioyl)hydrazono)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

ethyl 4-(9,10-dioxo-9,10-dihydroanthracen-1-yl)-2-hydroxy-4-oxobut-2-enoate (1444102-93-5) + 4-(4-methylphenyl)-3-thiosemicarbazide (13278-67-6) → ethyl 4-(9,10-dioxo-9,10-dihydroanthracen-1-yl)-4-oxo-2-(2-(p-tolylcarbamothioyl)hydrazono)butanoate (1444103-02-9) + ethyl 4-(9,10-dioxo-9,10-dihydroanthracen-1-yl)-4-oxo-2-(2-(p-tolylcarbamothioyl)hydrazono)butanoate (1444103-10-9)

Guidance literature:

In ethanol; for 4h; Reflux;

DOI:10.1016/j.ejmech.2013.03.071

Reference yield:

anthracene (120-12-7) → ethyl 4-(9,10-dioxo-9,10-dihydroanthracen-1-yl)-4-oxo-2-(2-(p-tolylcarbamothioyl)hydrazono)butanoate (1444103-02-9) + ethyl 4-(9,10-dioxo-9,10-dihydroanthracen-1-yl)-4-oxo-2-(2-(p-tolylcarbamothioyl)hydrazono)butanoate (1444103-10-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: aluminum (III) chloride / dichloromethane / 2 h / 0 °C

2.1: chromium(VI) oxide; acetic acid / 0.08 h / Reflux

3.1: sodium ethanolate / ethanol; 1,4-dioxane / 1 h / 20 °C

3.2: 1 h / 20 °C / pH 2

4.1: ethanol / 4 h / Reflux

With chromium(VI) oxide; aluminum (III) chloride; sodium ethanolate; acetic acid; In 1,4-dioxane; ethanol; dichloromethane;

DOI:10.1016/j.ejmech.2013.03.071

Reference yield:

1-acetylanthracene (7396-21-6) → ethyl 4-(9,10-dioxo-9,10-dihydroanthracen-1-yl)-4-oxo-2-(2-(p-tolylcarbamothioyl)hydrazono)butanoate (1444103-02-9) + ethyl 4-(9,10-dioxo-9,10-dihydroanthracen-1-yl)-4-oxo-2-(2-(p-tolylcarbamothioyl)hydrazono)butanoate (1444103-10-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: chromium(VI) oxide; acetic acid / 0.08 h / Reflux

2.1: sodium ethanolate / ethanol; 1,4-dioxane / 1 h / 20 °C

2.2: 1 h / 20 °C / pH 2

3.1: ethanol / 4 h / Reflux

With chromium(VI) oxide; sodium ethanolate; acetic acid; In 1,4-dioxane; ethanol;

DOI:10.1016/j.ejmech.2013.03.071

upstream raw materials:

anthracene

1-acetylanthracene

ethyl 4-(9,10-dioxo-9,10-dihydroanthracen-1-yl)-2-hydroxy-4-oxobut-2-enoate

4-(4-methylphenyl)-3-thiosemicarbazide