5-(2,5-dimethoxyphenyl)-2'-deoxyuridine 5'-phosphate bis triethylammonium salt

Base Information

• Chemical Name: 5-(2,5-dimethoxyphenyl)-2'-deoxyuridine 5'-phosphate bis triethylammonium salt
• CAS No.: 87414-27-5
• Molecular Formula: 2C₆H₁₅N*C₁₇H₂₁N₂O₁₀P
• Molecular Weight: 646.718
• Mol file: 87414-27-5.mol

Synonyms:5-(2,5-dimethoxyphenyl)-2'-deoxyuridine 5'-phosphate bis triethylammonium salt

Chemical Property of 5-(2,5-dimethoxyphenyl)-2'-deoxyuridine 5'-phosphate bis triethylammonium salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(2,5-dimethoxyphenyl)-2'-deoxyuridine 5'-phosphate bis triethylammonium salt

There total 1 articles about 5-(2,5-dimethoxyphenyl)-2'-deoxyuridine 5'-phosphate bis triethylammonium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

triethylamine carbonate (15715-58-9) + 5-(2,5-dimethoxyphenyl)-2'-deoxyuridine (76756-32-6) → 5-(2,5-dimethoxyphenyl)-2'-deoxyuridine 5'-phosphate bis triethylammonium salt (87414-27-5)

Guidance literature:

With pyridine; water; trichlorophosphate; In acetonitrile; at 0 ℃; for 10h;

DOI:10.1021/jm00361a016

Reference yield: 54.0%

5-(2,5-dimethoxyphenyl)-2'-deoxyuridine 5'-phosphate bis triethylammonium salt (87414-27-5) → 5-p-benzoquinonyl-2'-deoxyuridine 5'-phosphate (87414-22-0)

Guidance literature:

With silver(II) oxide; nitric acid; In water; for 0.166667h;

DOI:10.1021/jm00361a016

Reference yield:

5-(2,5-dimethoxyphenyl)-2'-deoxyuridine 5'-phosphate bis triethylammonium salt (87414-27-5) → Phosphoric acid mono-{(2R,3S,5R)-5-[5-(2,5-dihydroxy-phenyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-3-hydroxy-tetrahydro-furan-2-ylmethyl} ester (87414-28-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 54 percent / silver(II) oxide, 6N nitric acid / H₂O / 0.17 h

2: sodium borohydride / H₂O

With silver(II) oxide; sodium tetrahydroborate; nitric acid; In water;

DOI:10.1021/jm00361a016

upstream raw materials:

triethylamine carbonate

5-(2,5-dimethoxyphenyl)-2'-deoxyuridine

Downstream raw materials:

5-p-benzoquinonyl-2'-deoxyuridine 5'-phosphate

Phosphoric acid mono-{(2R,3S,5R)-5-[5-(2,5-dihydroxy-phenyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-3-hydroxy-tetrahydro-furan-2-ylmethyl} ester