Hydrazinecarbothioamide, N-2-benzothiazolyl- (9CI)

Base Information

• Chemical Name: Hydrazinecarbothioamide, N-2-benzothiazolyl- (9CI)
• CAS No.: 68372-14-5
• Molecular Formula: C₈H₈N₄S₂
• Molecular Weight: 224.31
• Mol file: 68372-14-5.mol

Synonyms:4-(benzothiazol-2-yl)thiosemicarbazide

Chemical Property of Hydrazinecarbothioamide, N-2-benzothiazolyl- (9CI)

Chemical Property:

Purity/Quality:

3-AMINO-1-(1,3-BENZOTHIAZOL-2-YL)THIOUREA 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Hydrazinecarbothioamide, N-2-benzothiazolyl- (9CI)

There total 3 articles about Hydrazinecarbothioamide, N-2-benzothiazolyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C8H6N2S3 (87561-50-0) → 4-(benzothiazol-2-yl)thiosemicarbazide (68372-14-5)

Guidance literature:

With hydrazine hydrate; In tetrahydrofuran; at 60 ℃; for 1h;

Reference yield:

2-amino-benzothiazole-6-sulfonic acid amide (18101-58-1) → 4-(benzothiazol-2-yl)thiosemicarbazide (68372-14-5)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide / tetrahydrofuran / 1 h / 60 °C

2: hydrazine hydrate / tetrahydrofuran / 1 h / 60 °C

With hydrazine hydrate; potassium hydroxide; In tetrahydrofuran;

Reference yield:

sulfanilamide (63-74-1) → 4-(benzothiazol-2-yl)thiosemicarbazide (68372-14-5)

Guidance literature:

Multi-step reaction with 3 steps

1: bromine; acetic acid

2: potassium hydroxide / tetrahydrofuran / 1 h / 60 °C

3: hydrazine hydrate / tetrahydrofuran / 1 h / 60 °C

With bromine; hydrazine hydrate; acetic acid; potassium hydroxide; In tetrahydrofuran;

upstream raw materials:

C₈H₆N₂S₃

2-amino-benzothiazole-6-sulfonic acid amide

sulfanilamide

Refernces