tert-butyl 3-(5-chloro-4-(2-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbonyl)hydrazinecarbonyl)-2-fluorophenyl)propanoate

Base Information

Chemical Name:tert-butyl 3-(5-chloro-4-(2-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbonyl)hydrazinecarbonyl)-2-fluorophenyl)propanoate
CAS No.:1228376-49-5
Molecular Formula:C₂₃H₂₀Cl₂F₄N₄O₄
Molecular Weight:563.336
Hs Code.:

Synonyms:tert-butyl 3-(5-chloro-4-(2-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbonyl)hydrazinecarbonyl)-2-fluorophenyl)propanoate

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Chemical Property of tert-butyl 3-(5-chloro-4-(2-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbonyl)hydrazinecarbonyl)-2-fluorophenyl)propanoate

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Technology Process of tert-butyl 3-(5-chloro-4-(2-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbonyl)hydrazinecarbonyl)-2-fluorophenyl)propanoate

There total 1 articles about tert-butyl 3-(5-chloro-4-(2-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbonyl)hydrazinecarbonyl)-2-fluorophenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 883032-94-8
8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbohydrazide

: 1228376-48-4
4-(3-tert-butoxy-3-oxopropyl)-2-chloro-5-fluorobenzoic acid

: 1228376-49-5
tert-butyl 3-(5-chloro-4-(2-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbonyl)hydrazinecarbonyl)-2-fluorophenyl)propanoate

Guidance literature:: 8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbohydrazide; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 0.333333h;

4-(3-tert-butoxy-3-oxopropyl)-2-chloro-5-fluorobenzoic acid; In N,N-dimethyl-formamide; at 20 ℃; for 12h;

Reference yield: 43.0%

: 1228376-49-5
tert-butyl 3-(5-chloro-4-(2-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbonyl)hydrazinecarbonyl)-2-fluorophenyl)propanoate

: 1228375-43-6
tert-butyl 3-(5-chloro-4-(5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,3,4-thiadiazol-2-yl)-2-fluorophenyl)propanoate

Guidance literature:: tert-butyl 3-(5-chloro-4-(2-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbonyl)hydrazinecarbonyl)-2-fluorophenyl)propanoate; With Lawessons reagent; pyridine; In toluene; at 20 ℃; Reflux;

With pyridine; tetraphosphorus decasulfide; at 20 - 110 ℃; for 2h;