2-[(allylmethyl-amino)-methyl]-5-chloro-4-fluoro-phenylamine

Base Information

• Chemical Name: 2-[(allylmethyl-amino)-methyl]-5-chloro-4-fluoro-phenylamine
• CAS No.: 855995-87-8
• Molecular Formula: C₁₁H₁₄ClFN₂
• Molecular Weight: 228.697
• Mol file: 855995-87-8.mol

Synonyms:2-[(allylmethyl-amino)-methyl]-5-chloro-4-fluoro-phenylamine

Chemical Property of 2-[(allylmethyl-amino)-methyl]-5-chloro-4-fluoro-phenylamine

Chemical Property:

Purity/Quality:

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Technology Process of 2-[(allylmethyl-amino)-methyl]-5-chloro-4-fluoro-phenylamine

There total 1 articles about 2-[(allylmethyl-amino)-methyl]-5-chloro-4-fluoro-phenylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

allyl-(4-chloro-5-fluoro-2-nitro-benzyl)-methyl-amine (855995-86-7) → 2-[(allylmethyl-amino)-methyl]-5-chloro-4-fluoro-phenylamine (855995-87-8)

Guidance literature:

With iron; ammonium chloride; In water; toluene; Heating / reflux;

Reference yield:

2-[(allylmethyl-amino)-methyl]-5-chloro-4-fluoro-phenylamine (855995-87-8) + 4,6-dichloropyrido<3,2-d>pyrimidine (175358-02-8) → {2-[(allyl-methyl-amino)-methyl]-5-chloro-4-fluoro-phenyl}-(6-chloro-pyrido [3,2-d] pyrimidin-4-yl)-amine (855995-88-9)

Guidance literature:

With triethylamine; In acetonitrile; for 5h; Heating / reflux;

upstream raw materials:

allyl-(4-chloro-5-fluoro-2-nitro-benzyl)-methyl-amine

Downstream raw materials:

{2-[(allyl-methyl-amino)-methyl]-5-chloro-4-fluoro-phenyl}-(6-chloro-pyrido [3,2-d] pyrimidin-4-yl)-amine