1-(1'-benzylspiro[indoline-3,4'-piperidine]-4-yl)ethanol dihydrochloride

Base Information

Chemical Name:1-(1'-benzylspiro[indoline-3,4'-piperidine]-4-yl)ethanol dihydrochloride
CAS No.:1172693-39-8
Molecular Formula:C₂₁H₂₆N₂O
Molecular Weight:322.45
Hs Code.:

Synonyms:1-(1'-benzylspiro[indoline-3,4'-piperidine]-4-yl)ethanol dihydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(1'-benzylspiro[indoline-3,4'-piperidine]-4-yl)ethanol dihydrochloride

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Technology Process of 1-(1'-benzylspiro[indoline-3,4'-piperidine]-4-yl)ethanol dihydrochloride

There total 1 articles about 1-(1'-benzylspiro[indoline-3,4'-piperidine]-4-yl)ethanol dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1172589-36-4
tert-butyl 1'-benzyl-4-(1-hydroxyethyl)spiro[indoline-3,4'-piperidine]-1-carboxylate

: 1172693-39-8
1-(1'-benzylspiro[indoline-3,4'-piperidine]-4-yl)ethanol dihydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 4h;

Reference yield: 31.0%

: 953045-35-7
(R)-4-chloro-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine

: 1172693-39-8
1-(1'-benzylspiro[indoline-3,4'-piperidine]-4-yl)ethanol dihydrochloride

: 1172589-38-6
1-(1'-benzyl-1-((R)-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)spiro[indoline-3,4'-piperidine]-4-yl)ethanol

Guidance literature:: With caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; palladium diacetate; In toluene; at 20 - 100 ℃;