3-{4-[2-(N-BOC-piperidin-4-yl)ethoxy]benzoylamino}-2(S)-benzenesulfonylaminopropionic acid

Base Information

Chemical Name:3-{4-[2-(N-BOC-piperidin-4-yl)ethoxy]benzoylamino}-2(S)-benzenesulfonylaminopropionic acid
CAS No.:298692-92-9
Molecular Formula:C₂₈H₃₇N₃O₈S
Molecular Weight:575.683
Hs Code.:

Synonyms:3-{4-[2-(N-BOC-piperidin-4-yl)ethoxy]benzoylamino}-2(S)-benzenesulfonylaminopropionic acid

Suppliers and Price of 3-{4-[2-(N-BOC-piperidin-4-yl)ethoxy]benzoylamino}-2(S)-benzenesulfonylaminopropionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-{4-[2-(N-BOC-piperidin-4-yl)ethoxy]benzoylamino}-2(S)-benzenesulfonylaminopropionic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-{4-[2-(N-BOC-piperidin-4-yl)ethoxy]benzoylamino}-2(S)-benzenesulfonylaminopropionic acid

There total 5 articles about 3-{4-[2-(N-BOC-piperidin-4-yl)ethoxy]benzoylamino}-2(S)-benzenesulfonylaminopropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 156185-87-4
N-phenylsulfonyl-L-asparagine

: 298692-92-9
3-{4-[2-(N-BOC-piperidin-4-yl)ethoxy]benzoylamino}-2(S)-benzenesulfonylaminopropionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 24 percent / aq. NaOH; Br₂ / 0.83 h / 0 - 90 °C

2: 45 percent / NEt₃; BOP / dimethylformamide / 20 h / 0 °C

With sodium hydroxide; bromine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide; 1: Hofmann degradation / 2: Condensation;
DOI:10.1021/jm000133v

Reference yield:

: 99-76-3,156291-94-0
methyl 4-hydroxylbenzoate

: 298692-92-9
3-{4-[2-(N-BOC-piperidin-4-yl)ethoxy]benzoylamino}-2(S)-benzenesulfonylaminopropionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / PPh₃; DEAD / tetrahydrofuran; toluene / 20 h / 20 °C

2: 95 percent / NaOH / ethanol / 20 h / 20 °C

3: 45 percent / NEt₃; BOP / dimethylformamide / 20 h / 0 °C

With sodium hydroxide; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide; toluene; 1: Condensation / 2: saponification / 3: Condensation;
DOI:10.1021/jm000133v

Reference yield:

: 89151-44-0
4-(2-hydroxyethyl)piperidine-1-carboxylic acid tert-butyl ester

: 298692-92-9
3-{4-[2-(N-BOC-piperidin-4-yl)ethoxy]benzoylamino}-2(S)-benzenesulfonylaminopropionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / PPh₃; DEAD / tetrahydrofuran; toluene / 20 h / 20 °C

2: 95 percent / NaOH / ethanol / 20 h / 20 °C

3: 45 percent / NEt₃; BOP / dimethylformamide / 20 h / 0 °C

With sodium hydroxide; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide; toluene; 1: Condensation / 2: saponification / 3: Condensation;
DOI:10.1021/jm000133v