[3,4,8-13C₃]daidzein

Base Information

• Chemical Name: [3,4,8-13C₃]daidzein
• CAS No.: 680182-24-5
• Molecular Formula: C₁₅H₁₀O₄
• Molecular Weight: 257.209
• Mol file: 680182-24-5.mol

Synonyms:[3,4,8-13C₃]daidzein

Chemical Property of [3,4,8-13C₃]daidzein

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [3,4,8-13C₃]daidzein

There total 6 articles about [3,4,8-13C₃]daidzein which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

N,N-dimethyl-formamide dimethyl acetal (4637-24-5) + [1,2,3'-13C3]-1-(2',4'-dihydroxyphenyl)-2-(4''-hydroxyphenyl)ethanone (680182-23-4) → [3,4,8-13C3]daidzein (680182-24-5)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 3h;

DOI:10.1016/j.tet.2003.12.033

Reference yield:

4'-benzyloxyphenyl-[1,2-(13)C2]acetonitrile (680182-20-1) → [3,4,8-13C3]daidzein (680182-24-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 98 percent / sodium hydroxide / H₂O / 6 h / Heating

2: 96 percent / hydrogen / palladium on carbon / ethyl acetate / 20 °C

3: 55 percent / boron trifluoride diethyl etherate / 3 h / 70 - 80 °C

4: 80 percent / dimethylformamide / 3 h / 20 °C

With sodium hydroxide; boron trifluoride diethyl etherate; hydrogen; palladium on activated charcoal; In water; ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2003.12.033

Reference yield:

4'-benzyloxy[1,2-13C2]phenylacetic acid (680182-21-2) → [3,4,8-13C3]daidzein (680182-24-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 96 percent / hydrogen / palladium on carbon / ethyl acetate / 20 °C

2: 55 percent / boron trifluoride diethyl etherate / 3 h / 70 - 80 °C

3: 80 percent / dimethylformamide / 3 h / 20 °C

With boron trifluoride diethyl etherate; hydrogen; palladium on activated charcoal; In ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2003.12.033

upstream raw materials:

N,N-dimethyl-formamide dimethyl acetal

[1,2,3'-13C₃]-1-(2',4'-dihydroxyphenyl)-2-(4''-hydroxyphenyl)ethanone

[2-⁽¹³⁾C]resorcinol

4'-hydroxy[1,2-13C₂]phenylacetic acid

Downstream raw materials:

[3,4,8-¹³C₃]-equol