2-(3,4-dimethoxyphenyl)-5-[[9-[2-(N-tert-butoxycarbonyl)amino]fluorenyl]amino]-2-(methylethyl)pentanenitrile

Base Information

• Chemical Name: 2-(3,4-dimethoxyphenyl)-5-[[9-[2-(N-tert-butoxycarbonyl)amino]fluorenyl]amino]-2-(methylethyl)pentanenitrile
• CAS No.: 387392-91-8
• Molecular Formula: C₃₄H₄₁N₃O₄
• Molecular Weight: 555.717

Synonyms:2-(3,4-dimethoxyphenyl)-5-[[9-[2-(N-tert-butoxycarbonyl)amino]fluorenyl]amino]-2-(methylethyl)pentanenitrile

Chemical Property of 2-(3,4-dimethoxyphenyl)-5-[[9-[2-(N-tert-butoxycarbonyl)amino]fluorenyl]amino]-2-(methylethyl)pentanenitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(3,4-dimethoxyphenyl)-5-[[9-[2-(N-tert-butoxycarbonyl)amino]fluorenyl]amino]-2-(methylethyl)pentanenitrile

There total 3 articles about 2-(3,4-dimethoxyphenyl)-5-[[9-[2-(N-tert-butoxycarbonyl)amino]fluorenyl]amino]-2-(methylethyl)pentanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.4%

D 620 (27487-66-7) + 2-(N-tert-butoxycarbonyl)amino-9-fluorenone (387392-90-7) → 2-(3,4-dimethoxyphenyl)-5-[[9-[2-(N-tert-butoxycarbonyl)amino]fluorenyl]amino]-2-(methylethyl)pentanenitrile (387392-91-8)

Guidance literature:

D 620; 2-(N-tert-butoxycarbonyl)amino-9-fluorenone; With titanium(IV) isopropylate; at 20 ℃;

With sodium cyanoborohydride; at 20 ℃; for 20h;

DOI:10.1016/S0968-0896(01)00191-2

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → 2-(3,4-dimethoxyphenyl)-5-[[9-[2-(N-tert-butoxycarbonyl)amino]fluorenyl]amino]-2-(methylethyl)pentanenitrile (387392-91-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 41 percent / triethylamine / dioxane / 48 h / 100 °C

2.1: titanium(IV) isopropoxide / 20 °C

2.2: 66.4 percent / sodium cyanoborohydride / 20 h / 20 °C

With titanium(IV) isopropylate; triethylamine; In 1,4-dioxane;

DOI:10.1016/S0968-0896(01)00191-2

Reference yield:

2-amino-9-fluorenone (3096-57-9) → 2-(3,4-dimethoxyphenyl)-5-[[9-[2-(N-tert-butoxycarbonyl)amino]fluorenyl]amino]-2-(methylethyl)pentanenitrile (387392-91-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 41 percent / triethylamine / dioxane / 48 h / 100 °C

2.1: titanium(IV) isopropoxide / 20 °C

2.2: 66.4 percent / sodium cyanoborohydride / 20 h / 20 °C

With titanium(IV) isopropylate; triethylamine; In 1,4-dioxane;

DOI:10.1016/S0968-0896(01)00191-2

upstream raw materials:

D 620

2-(N-tert-butoxycarbonyl)amino-9-fluorenone

di-tert-butyl dicarbonate

2-amino-9-fluorenone

Downstream raw materials:

2-(3,4-dimethoxyphenyl)-5-[[9-[2-(N-tert-butoxcarbonyl)amino]fluorenyl]-N-methyamino]-2-(methylethyl)pentanenitrile

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 387392-91-8 2-(3,4-dimethoxyphenyl)-5-[[9-[2-(N-tert-butoxycarbonyl)amino]fluorenyl]amino]-2-(methylethyl)pentanenitrile

Send

Send

Metric Ton KG G Pound L ML

Send

Send