Teichomycin A2

Base Information

• Chemical Name: Teichomycin A2
• CAS No.: 61036-64-4
• Molecular Formula: C78H77Cl2N8O32R
• Molecular Weight: 1709.39
• European Community (EC) Number: 612-067-9
• Mol file: 61036-64-4.mol

Synonyms:Targocid;Teichomycin;Teichomycin A2;Teicoplanin

Chemical Property of Teichomycin A2

Chemical Property:

• Appearance/Colour: Amorphous powder
• Melting Point: 260 ºC
• PSA: 671.64000
• LogP: 4.28220
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility.: DMSO (Sparingly, Heated), Water (Slightly)
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 24
• Hydrogen Bond Acceptor Count: 35
• Rotatable Bond Count: 20
• Exact Mass: 1919.5671466
• Heavy Atom Count: 135
• Complexity: 4070

Purity/Quality:

99% ^*data from raw suppliers

TeicoplaninA2(Mixtureof2-1,2-2,2-3,2-4and2-5) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCC=CCCC(=O)NC1C(C(C(OC1OC2=C3C=C4C=C2OC5=C(C=C(C=C5)C(C6C(=O)NC(C7=C(C(=CC(=C7)O)OC8C(C(C(C(O8)CO)O)O)O)C9=C(C=CC(=C9)C(C(=O)N6)NC(=O)C4NC(=O)C1C2=CC(=C(C(=C2)OC2=C(C=CC(=C2)C(C(=O)NC(C(C2=CC(=C(O3)C=C2)Cl)O)C(=O)N1)N)O)C)O)O)C(=O)OC)OC1C(C(C(C(O1)CO)O)O)NC(=O)C)Cl)CO)O)O
• Isomeric SMILES: CCCCC/C=C/CCC(=O)NC1C(C(C(OC1OC2=C3C=C4C=C2OC5=C(C=C(C=C5)C(C6C(=O)NC(C7=C(C(=CC(=C7)O)OC8C(C(C(C(O8)CO)O)O)O)C9=C(C=CC(=C9)C(C(=O)N6)NC(=O)C4NC(=O)C1C2=CC(=C(C(=C2)OC2=C(C=CC(=C2)C(C(=O)NC(C(C2=CC(=C(O3)C=C2)Cl)O)C(=O)N1)N)O)C)O)O)C(=O)OC)OC1C(C(C(C(O1)CO)O)O)NC(=O)C)Cl)CO)O)O
• Recent EU Clinical Trials: A Multicenter, Open-Label, Evaluator-Blinded, Randomized Study to Evaluate the Safety and Tolerability of Single-Dose IV Oritavancin Versus Standard of Care for the Treatment of Pediatric Subjects with Acute Bacterial Skin And Skin Structure Infections
• Uses: Glycopeptide antibiotic complex produced by Actinoplanes teichomyceticus; structurally related to vancomycin. Comprised of 5 major components differentiated by a specific fatty acid moiety. Inhibits peptidoglycan synthesis in the cell wall of gram-positive bacteria.