Chlordimorine

Base Information

Chemical Name:Chlordimorine
CAS No.:494-14-4
Molecular Formula:C₁₉H₂₂ClNO₂
Molecular Weight:331.842
Hs Code.:
Mol file:494-14-4.mol

Synonyms:4-[3-(2-chloro-4-phenyl-phenoxy)propyl]morpholine;4-[3-(3-chloro-biphenyl-4-yloxy)-propyl]-morpholine;4-[3-(3-Chlor-biphenyl-4-yloxy)-propyl]-morpholin;<2-Chlor-4-phenyl-phenyl>-<3-morpholino-propyl>-aether;

Suppliers and Price of Chlordimorine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-(3-[(3-CHLORO[1,1'-BIPHENYL]-4-YL)OXY]PROPYL)MORPHOLINE 95.00%
5MG
$ 495.64

Total 5 raw suppliers

Chemical Property of Chlordimorine

Chemical Property:

Vapor Pressure:1.54E-09mmHg at 25°C
Boiling Point:484.4°Cat760mmHg
Flash Point:246.8°C
PSA：21.70000
Density:1.151g/cm³
LogP:4.04600

Purity/Quality:

99% ^*data from raw suppliers

4-(3-[(3-CHLORO[1,1'-BIPHENYL]-4-YL)OXY]PROPYL)MORPHOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Chlordimorine

There total 4 articles about Chlordimorine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 95947-66-3
4-(3-biphenyl-4-yloxy-propyl)-morpholine

: 494-14-4
4-(3-((3-chloro-[1,1'-biphenyl]-4-yl)oxy)propyl)morpholine

Guidance literature:: With tetraethylammonium chloride; trichloroacetonitrile; In acetonitrile; at 23 ℃; for 2h; Electrochemical reaction; Inert atmosphere;
DOI:10.1021/acs.orglett.1c00704

Reference yield:

: 92-69-3
4-Phenylphenol

: 494-14-4
4-(3-((3-chloro-[1,1'-biphenyl]-4-yl)oxy)propyl)morpholine

Guidance literature:: Multi-step reaction with 3 steps

1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere

2: potassium carbonate / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

3: trichloroacetonitrile; tetraethylammonium chloride / acetonitrile / 2 h / 23 °C / Electrochemical reaction; Inert atmosphere

With di-isopropyl azodicarboxylate; tetraethylammonium chloride; potassium carbonate; trichloroacetonitrile; triphenylphosphine; In tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/acs.orglett.1c00704

Reference yield:

: 113795-28-1
4-(3-bromopropoxy)-1,1′-biphenyl

: 494-14-4
4-(3-((3-chloro-[1,1'-biphenyl]-4-yl)oxy)propyl)morpholine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

2: trichloroacetonitrile; tetraethylammonium chloride / acetonitrile / 2 h / 23 °C / Electrochemical reaction; Inert atmosphere

With tetraethylammonium chloride; potassium carbonate; trichloroacetonitrile; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/acs.orglett.1c00704