(5R)-5-<(1,3-Dioxolan-2-yl)methyl>-2,6,6-trimethylcyclohex-2-enon

Base Information

• Chemical Name: (5R)-5-<(1,3-Dioxolan-2-yl)methyl>-2,6,6-trimethylcyclohex-2-enon
• CAS No.: 123392-98-3
• Molecular Formula: C₁₃H₂₀O₃
• Molecular Weight: 224.3
• Mol file: 123392-98-3.mol

Synonyms:(5R)-5-<(1,3-Dioxolan-2-yl)methyl>-2,6,6-trimethylcyclohex-2-enon

Chemical Property of (5R)-5-<(1,3-Dioxolan-2-yl)methyl>-2,6,6-trimethylcyclohex-2-enon

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (5R)-5-<(1,3-Dioxolan-2-yl)methyl>-2,6,6-trimethylcyclohex-2-enon

There total 3 articles about (5R)-5-<(1,3-Dioxolan-2-yl)methyl>-2,6,6-trimethylcyclohex-2-enon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

(5R)-5-<(1,3-Dioxolan-2-yl)methyl>-2,6,6-trimethylcyclohex-2-enol → (5R)-5-<(1,3-Dioxolan-2-yl)methyl>-2,6,6-trimethylcyclohex-2-enon (123392-98-3)

Guidance literature:

With chromium(III) oxide; In pyridine; water; for 14h;

DOI:10.1002/hlca.19890720120

Reference yield:

(4R)-4-<(1,3-Dioxolan-2-yl)methyl>-1,3,3-trimethyl-1,2-epoxycyclohexan → (5R)-5-<(1,3-Dioxolan-2-yl)methyl>-2,6,6-trimethylcyclohex-2-enon (123392-98-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 43 percent / Filtrol / dioxane / 0.75 h / Ambient temperature

2: 79 percent / Cr₂O₃ / pyridine; H₂O / 14 h

With chromium(III) oxide; FILTROL; In 1,4-dioxane; pyridine; water;

DOI:10.1002/hlca.19890720120

Reference yield:

2-<<(R)-2',2',4'-trimethyl-3'-cyclohexenyl>methyl>-1,3-dioxolane (108361-19-9) → (5R)-5-<(1,3-Dioxolan-2-yl)methyl>-2,6,6-trimethylcyclohex-2-enon (123392-98-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 61 percent / 7 percent NaHCO₃, m-chloroperbenzoic acid / CH₂Cl₂ / 0.83 h / Heating

2: 43 percent / Filtrol / dioxane / 0.75 h / Ambient temperature

3: 79 percent / Cr₂O₃ / pyridine; H₂O / 14 h

With chromium(III) oxide; FILTROL; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In 1,4-dioxane; pyridine; dichloromethane; water;

DOI:10.1002/hlca.19890720120

upstream raw materials:

2-<<(R)-2',2',4'-trimethyl-3'-cyclohexenyl>methyl>-1,3-dioxolane

Downstream raw materials:

Ethyl-(1'R,5'R)-2-Methyl-4-<4'6'6'-trimethyl-5'-(3''-oxobut-1''-enyl)cyclohex-3'-enyl>but-2-enoat

(1'R,5'R)-4-<5'-(1,3-Dioxolan-2-yl)methyl-2',6',6'-trimethylcyclohex-2'-enyl>but-3-en-2-on

(1R,5R)-5-(3'-oxobut-1'-enyl)-4,6,6-trimethylcyclohex-3-en-1-acetaldehyd