4-[4-[({(1S,2R)-2-[(tert-butoxycarbonyl)amino]cyclohexyl}amino)carbonyl]-2-(2,4-dichlorophenyl)-5-methyl-1H-imidazol-1-yl]phenyl 3,3,3-trifluoropropane-1-sulfonate

Base Information

Chemical Name:4-[4-[({(1S,2R)-2-[(tert-butoxycarbonyl)amino]cyclohexyl}amino)carbonyl]-2-(2,4-dichlorophenyl)-5-methyl-1H-imidazol-1-yl]phenyl 3,3,3-trifluoropropane-1-sulfonate
CAS No.:930283-26-4
Molecular Formula:C₃₁H₃₅Cl₂F₃N₄O₆S
Molecular Weight:719.609
Hs Code.:

4-[4-[({(1S,2R)-2-[(tert-butoxycarbonyl)amino]cyclohexyl}amino)carbonyl]-2-(2,4-dichlorophenyl)-5-methyl-1H-imidazol-1-yl]phenyl 3,3,3-trifluoropropane-1-sulfonate

Synonyms:4-[4-[({(1S,2R)-2-[(tert-butoxycarbonyl)amino]cyclohexyl}amino)carbonyl]-2-(2,4-dichlorophenyl)-5-methyl-1H-imidazol-1-yl]phenyl 3,3,3-trifluoropropane-1-sulfonate

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Chemical Property of 4-[4-[({(1S,2R)-2-[(tert-butoxycarbonyl)amino]cyclohexyl}amino)carbonyl]-2-(2,4-dichlorophenyl)-5-methyl-1H-imidazol-1-yl]phenyl 3,3,3-trifluoropropane-1-sulfonate

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Technology Process of 4-[4-[({(1S,2R)-2-[(tert-butoxycarbonyl)amino]cyclohexyl}amino)carbonyl]-2-(2,4-dichlorophenyl)-5-methyl-1H-imidazol-1-yl]phenyl 3,3,3-trifluoropropane-1-sulfonate

There total 1 articles about 4-[4-[({(1S,2R)-2-[(tert-butoxycarbonyl)amino]cyclohexyl}amino)carbonyl]-2-(2,4-dichlorophenyl)-5-methyl-1H-imidazol-1-yl]phenyl 3,3,3-trifluoropropane-1-sulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 845866-80-0
3,3,3-trifluoropropane-1-sulfonyl chloride

: 930283-25-3
tert-butyl [(1R,2S)-2-({[2-(2,4-dichlorophenyl)-1-(4-hydroxyphenyl)-5-methyl-1H-imidazol-4-yl]carbonyl}amino)cyclohexyl]carbamate

: 930283-26-4
4-[4-[({(1S,2R)-2-[(tert-butoxycarbonyl)amino]cyclohexyl}amino)carbonyl]-2-(2,4-dichlorophenyl)-5-methyl-1H-imidazol-1-yl]phenyl 3,3,3-trifluoropropane-1-sulfonate

Guidance literature:: With triethylamine; In dichloromethane; at -78 - 20 ℃; for 3h;

Reference yield:

: 930283-26-4
4-[4-[({(1S,2R)-2-[(tert-butoxycarbonyl)amino]cyclohexyl}amino)carbonyl]-2-(2,4-dichlorophenyl)-5-methyl-1H-imidazol-1-yl]phenyl 3,3,3-trifluoropropane-1-sulfonate

: 4-[4-[({(1S,2R)-2-aminocyclohexyl}amino)carbonyl]-2-(2,4-dichlorophenyl)-5-methyl-1H-imidazol-1-yl]phenyl 3,3,3-trifluoropropane-1-sulfonate

Guidance literature:: 4-[4-[({(1S,2R)-2-[(tert-butoxycarbonyl)amino]cyclohexyl}amino)carbonyl]-2-(2,4-dichlorophenyl)-5-methyl-1H-imidazol-1-yl]phenyl 3,3,3-trifluoropropane-1-sulfonate; With methanol; thionyl chloride; at 0 - 20 ℃; for 1h;

With sodium hydrogencarbonate; In dichloromethane; water;