(1S)-1-(2-chlorophenyl)-2,2-dimethylpropane-1,3-diol

Base Information

Chemical Name:(1S)-1-(2-chlorophenyl)-2,2-dimethylpropane-1,3-diol
CAS No.:133164-40-6
Molecular Formula:C₁₁H₁₅ClO₂
Molecular Weight:214.692
Hs Code.:
DSSTox Substance ID:DTXSID601220467

Synonyms:(1S)-1-(2-chlorophenyl)-2,2-dimethylpropane-1,3-diol;133164-40-6;(S)-1-(2-Chlorophenyl)-2,2-dimethylpropane-1,3-diol;DTXSID601220467;AKOS025392226;SS-4919;(1S)-1-(2-Chlorophenyl)-2,2-dimethyl-1,3-propanediol

Suppliers and Price of (1S)-1-(2-chlorophenyl)-2,2-dimethylpropane-1,3-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of (1S)-1-(2-chlorophenyl)-2,2-dimethylpropane-1,3-diol

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:214.0760574
Heavy Atom Count:14
Complexity:182

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(CO)C(C1=CC=CC=C1Cl)O
Isomeric SMILES:CC(C)(CO)[C@@H](C1=CC=CC=C1Cl)O

Technology Process of (1S)-1-(2-chlorophenyl)-2,2-dimethylpropane-1,3-diol

There total 3 articles about (1S)-1-(2-chlorophenyl)-2,2-dimethylpropane-1,3-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: (S)-(-)-3-(2-chlorophenyl)-3-hydroxy-2,2-dimethylpropanal

: 133164-40-6
(R)-(+)-1-(2'-chlorophenyl)-2,2-dimethyl-1,3-propanediol

Guidance literature:: With sodium tetrahydroborate; In methanol; at 20 ℃;

Reference yield: 70.0%

: 98674-86-3
(S)-(-)-4-(2-chlorophenyl)-5,5-dimethyl-2-hydroxy-1,3,2-dioxaphosphorinane-2-oxide

: 133164-40-6
(R)-(+)-1-(2'-chlorophenyl)-2,2-dimethyl-1,3-propanediol

Guidance literature:: With potassium hydroxide; In ethylene glycol; at 150 ℃; for 8h;

Reference yield:

: (S)-(-)-2-(2'-chlorophenyl)-3,3-dimethyloxetane

: 133164-40-6
(R)-(+)-1-(2'-chlorophenyl)-2,2-dimethyl-1,3-propanediol

: 139406-15-8
(S)-(-)-1-(2'-chlorophenyl)-2,2-dimethyl-1,3-propanediol

Guidance literature:: With sulfuric acid; for 24h; Product distribution; Heating; var. concentration reagents, var. times;
DOI:10.1016/0957-4166(95)00173-M