3-[(E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol

Base Information

Chemical Name:3-[(E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol
CAS No.:133683-37-1
Molecular Formula:C₁₈H₂₀O₂
Molecular Weight:268.356
Hs Code.:
Nikkaji Number:J366.316G
ChEMBL ID:CHEMBL181427
Mol file:133683-37-1.mol

Synonyms:3,4'-dihydroxy-alpha,beta-diethylstilbene;3,4-DABDS

Suppliers and Price of 3-[(E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-[(E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol

Chemical Property:

Boiling Point:422.5°Cat760mmHg
Flash Point:195.6°C
PSA：40.46000
Density:1.107g/cm³
LogP:4.82860
XLogP3:5.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:268.146329876
Heavy Atom Count:20
Complexity:326

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=C(CC)C1=CC(=CC=C1)O)C2=CC=C(C=C2)O
Isomeric SMILES:CC/C(=C(/CC)\C1=CC(=CC=C1)O)/C2=CC=C(C=C2)O

Technology Process of 3-[(E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol

There total 7 articles about 3-[(E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 752225-72-2
(E,Z)-(+/-)-3-(4-methoxyphenyl)-4-(3-methoxyphenyl)hex-2-ene

: (Z)-3-(4-hydroxyphenyl)-4-(3-hydroxyphenyl)hex-2-ene

: 133683-37-1
(E/Z)-3-(4-hydroxyphenyl)-4-(3-hydroxyphenyl)hex-3-ene

Guidance literature:: With boron tribromide; In dichloromethane; at -5 - 20 ℃; for 7h;
DOI:10.1016/j.bmcl.2004.06.098

Reference yield:

: 752225-72-2
(E,Z)-(+/-)-3-(4-methoxyphenyl)-4-(3-methoxyphenyl)hex-2-ene

: 133683-37-1
(E)-3-(4-hydroxyphenyl)-4-(3-hydroxyphenyl)hex-3-ene

: (Z)-3-(4-hydroxyphenyl)-4-(3-hydroxyphenyl)hex-2-ene

: (E)-3-(4-hydroxyphenyl)-4-(3-hydroxyphenyl)hex-2-ene

: (Z)-3-(4-hydroxyphenyl)-4-(3-hydroxyphenyl)hex-3-ene

Guidance literature:: With boron tribromide; In dichloromethane; at -5 - 20 ℃; for 7h; Title compound not separated from byproducts;
DOI:10.1002/ardp.200400904

Reference yield:

: 128349-58-6
(+/-)-1-(4-methoxyphenyl)-2-(3-methoxyphenyl)butan-1-one

: 133683-37-1
(E)-3-(4-hydroxyphenyl)-4-(3-hydroxyphenyl)hex-3-ene

Guidance literature:: Multi-step reaction with 2 steps

1.1: Mg tunings; iodine / diethyl ether / 1 h / Heating

1.2: 58 percent / diethyl ether / 2 h / Heating

2.1: BBr₃ / CH₂Cl₂ / 7 h / -5 - 20 °C

With iodine; boron tribromide; magnesium; In diethyl ether; dichloromethane; 1.1: Grignard reaction;
DOI:10.1002/ardp.200400904