1-[3-(bromomethyl)phenoxycarbonylaminomethyl]cyclohexaneacetic acid

Base Information

• Chemical Name: 1-[3-(bromomethyl)phenoxycarbonylaminomethyl]cyclohexaneacetic acid
• CAS No.: 713123-28-5
• Molecular Formula: C₁₇H₂₂BrNO₄
• Molecular Weight: 384.27
• Mol file: 713123-28-5.mol

Synonyms:1-[3-(bromomethyl)phenoxycarbonylaminomethyl]cyclohexaneacetic acid

Chemical Property of 1-[3-(bromomethyl)phenoxycarbonylaminomethyl]cyclohexaneacetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 1-[3-(bromomethyl)phenoxycarbonylaminomethyl]cyclohexaneacetic acid

There total 1 articles about 1-[3-(bromomethyl)phenoxycarbonylaminomethyl]cyclohexaneacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bis(trichloromethyl) carbonate (32315-10-9) + H-Gpn-OH (60142-96-3) → 1-[3-(bromomethyl)phenoxycarbonylaminomethyl]cyclohexaneacetic acid (713123-28-5)

Guidance literature:

bis(trichloromethyl) carbonate; m-hydroxybenzyl bromide; With N-ethyl-N,N-diisopropylamine; In methylene chloride; dichloromethane; at 20 ℃; for 12h;

for 2h; Heating / reflux;

H-Gpn-OH; With N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); for 3h;

Reference yield:

1-[3-(bromomethyl)phenoxycarbonylaminomethyl]cyclohexaneacetic acid (713123-28-5) → 1-[3-(nitrooxymethyl)phenoxycarbonylaminomethyl]cyclohexaneacetic acid (XXIIIA) (713123-27-4)

Guidance literature:

With silver nitrate; In acetonitrile; at 20 ℃; for 12h;

upstream raw materials:

bis(trichloromethyl) carbonate

H-Gpn-OH

Downstream raw materials:

1-[3-(nitrooxymethyl)phenoxycarbonylaminomethyl]cyclohexaneacetic acid (XXIIIA)