14,15-dinor-8α,12-epoxy-13-labdanone

Base Information

• Chemical Name: 14,15-dinor-8α,12-epoxy-13-labdanone
• CAS No.: 162599-53-3
• Molecular Formula: C₁₈H₃₀O₂
• Molecular Weight: 278.435
• Mol file: 162599-53-3.mol

Synonyms:14,15-dinor-8α,12-epoxy-13-labdanone

Chemical Property of 14,15-dinor-8α,12-epoxy-13-labdanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 14,15-dinor-8α,12-epoxy-13-labdanone

There total 2 articles about 14,15-dinor-8α,12-epoxy-13-labdanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

sclareol (515-03-7) → sclareol oxide (5153-92-4) + sclareolic acid methyl ester (110152-12-0) + (R)-2-hydroxy-4-((1R,2R,4aS,8aS)-2-hydroxy-2,5,5,8a-tetramethyldecahydronaphthalen-1-yl)-2-methylbutanal (143423-39-6) + 14,15-dinor-8α,12-epoxy-13-labdanone (162599-53-3)

Guidance literature:

With sodium periodate; ozone; In methanol; water; at 25 ℃; for 0.25h; Further byproducts given;

DOI:10.1016/0040-4039(94)88497-8

Reference yield: 25.0%

sclareol (515-03-7) → sclareol oxide (5153-92-4) + (1R,2R,8aS)-2,5,5,8a-tetramethyl-1-(2-oxoethyl)decahydronaphthalen-2-yl acetate (106672-01-9) + sclareolic acid methyl ester (110152-12-0) + (R)-2-hydroxy-4-((1R,2R,4aS,8aS)-2-hydroxy-2,5,5,8a-tetramethyldecahydronaphthalen-1-yl)-2-methylbutanal (143423-39-6) + 14,15-dinor-8α,12-epoxy-13-labdanone (162599-53-3)

Guidance literature:

With sodium periodate; ozone; In methanol; water; at 25 ℃; for 0.25h; Product distribution; various conditions investigated; further products;

DOI:10.1016/0040-4039(94)88497-8

Reference yield:

14,15-dinor-8α,12-epoxy-13-labdanone (162599-53-3) → (3aR)-(+)-sclareolide (564-20-5,1216-84-8,30450-17-0,58976-28-6,64090-92-2,67844-42-2,79768-41-5,79768-42-6,86688-27-9,86688-28-0,95406-08-9,98719-44-9,98719-46-1,131831-65-7,140851-80-5)

Guidance literature:

With oxygen; at 20 ℃;

DOI:10.1002/hlca.200490239

upstream raw materials:

sclareol

Downstream raw materials:

(3aR)-(+)-sclareolide

Refernces