Technology Process of 3'-hydroxy-3,4-methylenedioxy-2,4',5-trimethoxy-(E)-stilbene
There total 4 articles about 3'-hydroxy-3,4-methylenedioxy-2,4',5-trimethoxy-(E)-stilbene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
at 20 ℃;
for 1h;
DOI:10.1021/np1004278
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: tetrabutylammomium bromide; potassium hydroxide / 0.67 h / 100 °C
2.1: pyridine; ozone / methanol; chloroform / -15 - 0 °C
3.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere
3.2: 10 h / 20 °C / Inert atmosphere
4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C
With
pyridine; n-butyllithium; tetrabutyl ammonium fluoride; tetrabutylammomium bromide; ozone; potassium hydroxide;
In
tetrahydrofuran; methanol; hexane; chloroform;
3.1: Wittig reaction / 3.2: Wittig reaction;
DOI:10.1021/np1004278
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere
1.2: 10 h / 20 °C / Inert atmosphere
2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C
With
n-butyllithium; tetrabutyl ammonium fluoride;
In
tetrahydrofuran; hexane;
1.1: Wittig reaction / 1.2: Wittig reaction;
DOI:10.1021/np1004278
