1-(4-methoxyphenyl)-1,7-dicarba-closo-dodecaborane

Base Information

• Chemical Name: 1-(4-methoxyphenyl)-1,7-dicarba-closo-dodecaborane
• CAS No.: 111426-92-7
• Molecular Formula: C₉H₁₈B₁₀O
• Molecular Weight: 250.351
• Mol file: 111426-92-7.mol

Synonyms:1-(4-methoxyphenyl)-1,7-dicarba-closo-dodecaborane

Chemical Property of 1-(4-methoxyphenyl)-1,7-dicarba-closo-dodecaborane

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 1-(4-methoxyphenyl)-1,7-dicarba-closo-dodecaborane

There total 2 articles about 1-(4-methoxyphenyl)-1,7-dicarba-closo-dodecaborane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

1,7-dicarba-closo-dodecaborane(12) (16986-24-6) + para-iodoanisole (696-62-8) → 1-(4-methoxyphenyl)-1,7-dicarba-closo-dodecaborane (111426-92-7)

Guidance literature:

1,7-dicarba-closo-dodecaborane⁽¹²⁾; With n-butyllithium; In 1,2-dimethoxyethane;

para-iodoanisole; With pyridine; copper(l) chloride;

DOI:10.1016/j.bmcl.2015.05.083

Reference yield: 63.0%

1,7-dicarba-closo-dodecaborane(12) (16986-24-6) + 4-methoxybenzenediazonium tetrafluoroborate (459-64-3) → 1-(4-methoxyphenyl)-1,7-dicarba-closo-dodecaborane (111426-92-7)

Guidance literature:

With n-butyllithium; copper(l) chloride; In tetrahydrofuran; diethyl ether; hexane; under N2; dropwise addn. of BuLi in hexane to a soln. of m-carborane inether at 0-5°C with stirring, addn. of anhydr. CuCl with stirring, addn. of THF, heating at 40°C for 10 min, cooling to 0-5°C, addn. of BF4-salt.; addn. of MeOH at 20°C, filtn. of ppt., washing (benzene, ether),washing of filtrate (aq. HCl, H2O), drying (CaCl2 or Na2SO4), evapn. invac., TLC (Siloful, benzene-petroleum ether), recrystn. (MeOH), elem. anal.;

Reference yield: 91.0%

1-(4-methoxyphenyl)-1,7-dicarba-closo-dodecaborane (111426-92-7) → 1-(4-hydroxyphenyl)-1,7-dicarba-closo-dodecaborane (34376-82-4)

Guidance literature:

With boron tribromide; In dichloromethane; at 0 - 20 ℃; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.jorganchem.2015.05.029

upstream raw materials:

1,7-dicarba-closo-dodecaborane⁽¹²⁾

4-methoxybenzenediazonium tetrafluoroborate

para-iodoanisole

Downstream raw materials:

1-(4-hydroxyphenyl)-1,7-dicarba-closo-dodecaborane