Licarin B

Base Information

Chemical Name:Licarin B
CAS No.:51020-87-2
Molecular Formula:C₂₀H₂₀O₄
Molecular Weight:324.376
Hs Code.:
DSSTox Substance ID:DTXSID601317642
Nikkaji Number:J585.124F,J238.371C
Wikidata:Q104396883
Metabolomics Workbench ID:129883
ChEMBL ID:CHEMBL259386
Mol file:51020-87-2.mol

Synonyms:licarin B

Suppliers and Price of Licarin B

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
(-)-LicarinB >98%,StandardReferencesGrade
20 mg
$ 280.00

Crysdot
LicarinB 97%
25mg
$ 238.00

Crysdot
LicarinB 97%
50mg
$ 353.00

Crysdot
LicarinB 97%
100mg
$ 641.00

Chemenu
5-((2R,3R)-7-methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)benzo[d][1,3]dioxole 97%
100mg
$ 468.00

AvaChem
(-)-Licarin B
20mg
$ 189.00

AvaChem
(-)-Licarin B
5mg
$ 89.00

ApexBio Technology
(-)-LicarinB
20mg
$ 250.00

AK Scientific
licarinB
25mg
$ 336.00

Total 46 raw suppliers

Chemical Property of Licarin B

Chemical Property:

Vapor Pressure:3.78E-07mmHg at 25°C
Refractive Index:1.607
Boiling Point:428.5 °C at 760 mmHg
Flash Point:131.4 °C
PSA：36.92000
Density:1.201 g/cm³
LogP:4.69420
Storage Temp.:2-8°C
XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:324.13615911
Heavy Atom Count:24
Complexity:465

Purity/Quality:

≥98% ^*data from raw suppliers

(-)-LicarinB >98%,StandardReferencesGrade ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC=CC1=CC2=C(C(=C1)OC)OC(C2C)C3=CC4=C(C=C3)OCO4
Isomeric SMILES:C/C=C/C1=CC2=C(C(=C1)OC)O[C@H]([C@@H]2C)C3=CC4=C(C=C3)OCO4

Technology Process of Licarin B

There total 12 articles about Licarin B which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 140423-82-1,140423-83-2
threo-2-<2'-hydroxy-3'-methoxy-5'-(1-propenyl)>phenyl-1-piperonylpropanol

: 23342-98-5,42016-15-9,51020-87-2,55515-49-6
(+/-)-licarin B

Guidance literature:: With acetic acid; for 1h; Heating;
DOI:10.1248/cpb.39.3123

Reference yield:

: 105494-65-3,66680-85-1,66680-84-0
(E)-propenyl-tri-n-butylstannane

: 5-((2S,3S)-5-Iodo-7-methoxy-3-methyl-2,3-dihydro-benzofuran-2-yl)-benzo[1,3]dioxole

: 23342-98-5,42016-15-9,51020-87-2,55515-49-6
(+/-)-licarin B

Guidance literature:: With tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; trifuran-2-yl-phosphane; lithium chloride; In N,N-dimethyl-formamide; at 120 - 130 ℃; Yield given;
DOI:10.1016/0040-4039(96)01619-X

Reference yield:

: 168648-79-1
N-(3-methoxy-4-oxo-2,5-cyclohexadien-1-ylidene)benzenesulfonamide

: 23342-98-5,42016-15-9,51020-87-2,55515-49-6
(+/-)-licarin B

Guidance literature:: Multi-step reaction with 7 steps

1: BF₃*Et₂O / CH₂Cl₂ / -78 °C

2: KOtBu / tetrahydrofuran / 60 - 70 °C

3: Na, anthracene / tetrahydrofuran / 23 °C

4: F₃CCO₂H / CH₂Cl₂ / 23 °C

5: 1.) NaNO₂, 50percent aq. HOAc, 2.) K₂CO₃ / 1.) 0 deg C, 2.) water, 0 deg C

6: Me₃SiCl, NaI / acetonitrile

7: Pd₂(dba)3, (2-furyl)3P, LiCl / dimethylformamide / 120 - 130 °C

With chloro-trimethyl-silane; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; trifuran-2-yl-phosphane; anthracene; boron trifluoride diethyl etherate; potassium tert-butylate; sodium; potassium carbonate; acetic acid; trifluoroacetic acid; sodium iodide; lithium chloride; sodium nitrite; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/0040-4039(96)01619-X