2-Benzyl-6-(4-methoxyphenyl)pyridazin-3-one

Base Information

Chemical Name:2-Benzyl-6-(4-methoxyphenyl)pyridazin-3-one
CAS No.:915878-67-0
Molecular Formula:C₁₈H₁₆N₂O₂
Molecular Weight:292.337
Hs Code.:
DSSTox Substance ID:DTXSID101325616
ChEMBL ID:CHEMBL1536040

Synonyms:2-benzyl-6-(4-methoxyphenyl)pyridazin-3-one;2-benzyl-6-(4-methoxyphenyl)pyridazin-3(2H)-one;MLS001163075;CHEMBL1536040;SCHEMBL23297368;DCWBECUIKSYRPT-UHFFFAOYSA-N;DTXSID101325616;HMS2823C05;STK928969;AKOS005659004;915878-67-0;SMR000499401;2-benzyl-6-(4-methoxyphenyl)-3(2H)-pyridazinone;F2774-0536

Suppliers and Price of 2-Benzyl-6-(4-methoxyphenyl)pyridazin-3-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Benzyl-6-(4-methoxyphenyl)pyridazin-3-one

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:292.121177757
Heavy Atom Count:22
Complexity:444

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NN(C(=O)C=C2)CC3=CC=CC=C3

Technology Process of 2-Benzyl-6-(4-methoxyphenyl)pyridazin-3-one

There total 3 articles about 2-Benzyl-6-(4-methoxyphenyl)pyridazin-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1344096-38-3
C₁₈H₁₈N₂O₂

: 915878-67-0
2-benzyl-6-(4-methoxyphenyl)pyridazin-3(2H)-one

Guidance literature:: With copper(II) choride dihydrate; oxygen; In dimethyl sulfoxide; at 20 - 120 ℃; for 0.166667h;
DOI:10.1080/00397911.2020.1731757

Reference yield:

: 1017-06-7
6-(4-Methoxyphenyl)-4,5-dihydro-2H-pyridazin-3-one

: 915878-67-0
2-benzyl-6-(4-methoxyphenyl)pyridazin-3(2H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C

2: iodine / dimethyl sulfoxide / 8 h / 100 °C

With iodine; sodium hydride; In dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1016/j.cclet.2011.07.019

Reference yield:

: 555-96-4
Benzylhydrazine

: 915878-67-0
2-benzyl-6-(4-methoxyphenyl)pyridazin-3(2H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: isopropyl alcohol / Reflux

2: manganese(IV) oxide / 5,5-dimethyl-1,3-cyclohexadiene / Reflux

With manganese(IV) oxide; In 5,5-dimethyl-1,3-cyclohexadiene; isopropyl alcohol;
DOI:10.1021/jm200401v