(2-Diphenylacetylamino-acetylamino)-acetic acid 16-[2-(2-diphenylacetylamino-acetylamino)-acetoxy]-hexadecyl ester

Base Information

• Chemical Name: (2-Diphenylacetylamino-acetylamino)-acetic acid 16-[2-(2-diphenylacetylamino-acetylamino)-acetoxy]-hexadecyl ester
• CAS No.: 196867-76-2
• Molecular Formula: C₅₂H₆₆N₄O₈
• Molecular Weight: 875.118
• Mol file: 196867-76-2.mol

Synonyms:(2-Diphenylacetylamino-acetylamino)-acetic acid 16-[2-(2-diphenylacetylamino-acetylamino)-acetoxy]-hexadecyl ester

Chemical Property of (2-Diphenylacetylamino-acetylamino)-acetic acid 16-[2-(2-diphenylacetylamino-acetylamino)-acetoxy]-hexadecyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-Diphenylacetylamino-acetylamino)-acetic acid 16-[2-(2-diphenylacetylamino-acetylamino)-acetoxy]-hexadecyl ester

There total 3 articles about (2-Diphenylacetylamino-acetylamino)-acetic acid 16-[2-(2-diphenylacetylamino-acetylamino)-acetoxy]-hexadecyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

1,16-hexadecanediol (7735-42-4) + (2-Diphenylacetylamino-acetylamino)-acetic acid ethyl ester (315199-22-5) → (2-Diphenylacetylamino-acetylamino)-acetic acid 16-[2-(2-diphenylacetylamino-acetylamino)-acetoxy]-hexadecyl ester (196867-76-2)

Guidance literature:

With 1,3-dichlorotetrabutyldistannoxane; In toluene; Heating;

DOI:10.1021/ja971224t

Reference yield:

diphenylacetic acid chloride (1871-76-7) → (2-Diphenylacetylamino-acetylamino)-acetic acid 16-[2-(2-diphenylacetylamino-acetylamino)-acetoxy]-hexadecyl ester (196867-76-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 97 percent / Et₃N / CHCl₃

2: 74 percent / (Bu₂ClSn)2O / toluene / Heating

With 1,3-dichlorotetrabutyldistannoxane; triethylamine; In chloroform; toluene;

DOI:10.1021/ja971224t

Reference yield:

glycylglycine ethyl ester (627-74-7) → (2-Diphenylacetylamino-acetylamino)-acetic acid 16-[2-(2-diphenylacetylamino-acetylamino)-acetoxy]-hexadecyl ester (196867-76-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 97 percent / Et₃N / CHCl₃

2: 74 percent / (Bu₂ClSn)2O / toluene / Heating

With 1,3-dichlorotetrabutyldistannoxane; triethylamine; In chloroform; toluene;

DOI:10.1021/ja971224t

upstream raw materials:

1,16-hexadecanediol

(2-Diphenylacetylamino-acetylamino)-acetic acid ethyl ester

diphenylacetic acid chloride

glycylglycine ethyl ester