(S)-tert-butyl-4-(4-(benzyloxycarbonylamino)butanamido)-3-((1R,3R)-2,2-dimethyl-3-(2-methyl-1,3-dioxolan-2-yl)cyclobutyl)butanoate

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Chemical Name:(S)-tert-butyl-4-(4-(benzyloxycarbonylamino)butanamido)-3-((1R,3R)-2,2-dimethyl-3-(2-methyl-1,3-dioxolan-2-yl)cyclobutyl)butanoate
CAS No.:1234493-08-3
Molecular Formula:C₃₀H₄₆N₂O₇
Molecular Weight:546.704
Hs Code.:

Synonyms:(S)-tert-butyl-4-(4-(benzyloxycarbonylamino)butanamido)-3-((1R,3R)-2,2-dimethyl-3-(2-methyl-1,3-dioxolan-2-yl)cyclobutyl)butanoate

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Chemical Property of (S)-tert-butyl-4-(4-(benzyloxycarbonylamino)butanamido)-3-((1R,3R)-2,2-dimethyl-3-(2-methyl-1,3-dioxolan-2-yl)cyclobutyl)butanoate

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Technology Process of (S)-tert-butyl-4-(4-(benzyloxycarbonylamino)butanamido)-3-((1R,3R)-2,2-dimethyl-3-(2-methyl-1,3-dioxolan-2-yl)cyclobutyl)butanoate

There total 1 articles about (S)-tert-butyl-4-(4-(benzyloxycarbonylamino)butanamido)-3-((1R,3R)-2,2-dimethyl-3-(2-methyl-1,3-dioxolan-2-yl)cyclobutyl)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 5105-78-2
4-(benzyloxycarbonylamino)butyric acid

: 454486-13-6
tert-butyl (S)-4-amino-3-[(1R,3R)-2,2-dimethyl-3-(2-methyl-1,3-dioxolan-2-yl)cyclobutyl]butanoate

: 1234493-08-3
(S)-tert-butyl-4-(4-(benzyloxycarbonylamino)butanamido)-3-((1R,3R)-2,2-dimethyl-3-(2-methyl-1,3-dioxolan-2-yl)cyclobutyl)butanoate

Guidance literature:: 4-(benzyloxycarbonylamino)butyric acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; for 0.333333h; Inert atmosphere;

tert-butyl (S)-4-amino-3-[(1R,3R)-2,2-dimethyl-3-(2-methyl-1,3-dioxolan-2-yl)cyclobutyl]butanoate; In N,N-dimethyl-formamide; at 20 ℃; for 21h; Inert atmosphere;
DOI:10.1021/ol1010664