asterone

Base Information

• Chemical Name: asterone
• CAS No.: 37717-02-5
• Molecular Formula: C₂₁H₃₂O₃
• Molecular Weight: 332.483
• Mol file: 37717-02-5.mol

Synonyms:3b,6a-Dihydroxy-5a-pregn-9(11)-en-20-one; 5a-Pregn-9(11)-en-20-one, 3b,6a-dihydroxy-; Asterone; Asterosapogenin I

Chemical Property of asterone

Chemical Property:

• Vapor Pressure: 2.8E-11mmHg at 25°C
• Boiling Point: 481.2°Cat760mmHg
• PKA: 14?+-.0.70(Predicted)
• Flash Point: 258.9°C
• PSA: 57.53000
• Density: 1.15g/cm³
• LogP: 3.48610

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of asterone

There total 19 articles about asterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-O-sulfo-asterone sodium salt → 3β,6α-dihydroxy-5α-pregn-9(11)-en-20-one (37717-02-5)

Guidance literature:

With pyridine; In 1,4-dioxane; at 100 ℃; for 2h;

DOI:10.1021/np000030f

Reference yield:

3β,6α-diacetoxy-5α-pregn-9(11)-en-20-one (37772-20-6) → 3β,6α-dihydroxy-5α-pregn-9(11)-en-20-one (37717-02-5)

Guidance literature:

With potassium hydroxide; In water; tert-butyl alcohol; at 30 ℃; for 17h;

DOI:10.1002/chem.201301186

Reference yield:

asterone 6-O-<β-D-fucopyranosyl-(1-2)-β-D-quinovopyranosyl-(1-4)-<β-D-quinovopyranosyl-(1-2)>-β-D-xylopyranosyl-(1-3)-β-D-quinovopyranoside> (88434-27-9) → 3β,6α-dihydroxy-5α-pregn-9(11)-en-20-one (37717-02-5) + C38H60O15 (139243-51-9) + C44H70O19 (139243-49-5) + 1-[(3S,5S,6S,8S,10S,13S,14S,17S)-3-Hydroxy-10,13-dimethyl-6-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-2,3,4,5,6,7,8,10,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-ethanone (63908-85-0)

Guidance literature:

With water; In 1,4-dioxane; at 140 ℃; for 24h; Further byproducts given;

upstream raw materials:

asterone 6-O-<β-D-fucopyranosyl-(1-2)-β-D-quinovopyranosyl-(1-4)-<β-D-quinovopyranosyl-(1-2)>-β-D-xylopyranosyl-(1-3)-β-D-quinovopyranoside>

C₅₆H₉₂O₂₅

asterone 6-O-<β-D-fucopyranosyl-(1-3)-β-D-fucopyranosyl-(1-2)-β-D-quinovopyranosyl-(1-4)-<β-D-quinovopyranosyl-(1-2)>-β-D-xylopyranosyl-(1-3)-β-D-quinovopyranoside>

C₃₇H₇₂O₄Si₃

Downstream raw materials:

C₄₁H₅₀Br₂O₆

asterogenol