3-chloromethyl-9-(2,5-dichlorobenzyl)-9H-β-carboline hydrochloride

Base Information

• Chemical Name: 3-chloromethyl-9-(2,5-dichlorobenzyl)-9H-β-carboline hydrochloride
• CAS No.: 274919-85-6
• Molecular Formula: C₁₉H₁₃Cl₃N₂*ClH
• Molecular Weight: 412.146
• Mol file: 274919-85-6.mol

Synonyms:3-chloromethyl-9-(2,5-dichlorobenzyl)-9H-β-carboline hydrochloride

Chemical Property of 3-chloromethyl-9-(2,5-dichlorobenzyl)-9H-β-carboline hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-chloromethyl-9-(2,5-dichlorobenzyl)-9H-β-carboline hydrochloride

There total 4 articles about 3-chloromethyl-9-(2,5-dichlorobenzyl)-9H-β-carboline hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[9-(2,5-dichlorobenzyl)-9H-β-carbolin-3-yl]methanol (274919-22-1) → 3-chloromethyl-9-(2,5-dichlorobenzyl)-9H-β-carboline hydrochloride (274919-85-6)

Guidance literature:

With thionyl chloride; In dichloromethane;

Reference yield:

methyl 9H-β-carboline-3-carboxylate (69954-48-9) → 3-chloromethyl-9-(2,5-dichlorobenzyl)-9H-β-carboline hydrochloride (274919-85-6)

Guidance literature:

Multi-step reaction with 3 steps

1: N,N-dimethyl-formamide

2: potassium hydroxide; sodium borohydrid / methanol; ethanol; chloroform

3: thionyl chloride / dichloromethane

With potassium hydroxide; thionyl chloride; sodium borohydrid; In methanol; ethanol; dichloromethane; chloroform; N,N-dimethyl-formamide;

Reference yield:

methyl 9-(2,5-dichlorobenzyl)-9H-β-carboline-3-carboxylate (274919-21-0) → 3-chloromethyl-9-(2,5-dichlorobenzyl)-9H-β-carboline hydrochloride (274919-85-6)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide; sodium borohydrid / methanol; ethanol; chloroform

2: thionyl chloride / dichloromethane

With potassium hydroxide; thionyl chloride; sodium borohydrid; In methanol; ethanol; dichloromethane; chloroform;

upstream raw materials:

[9-(2,5-dichlorobenzyl)-9H-β-carbolin-3-yl]methanol

methyl 9-(2,5-dichlorobenzyl)-9H-β-carboline-3-carboxylate

methyl 9H-β-carboline-3-carboxylate

1,4-Dichloro-2-chloromethyl-benzene

Downstream raw materials:

3-azidomethyl-9-(2,5-dichlorobenzyl)-9H-β-carboline

Refernces