Technology Process of 2-methyl-2,4,4-triphenyl-3-butenoyl azide
There total 6 articles about 2-methyl-2,4,4-triphenyl-3-butenoyl azide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium azide; tetrabutylammomium bromide;
In
dichloromethane; water;
at 0 ℃;
for 2h;
DOI:10.1021/jo034452g
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: BuLi / 1,2-dimethoxy-ethane; hexane / 1 h / 0 °C
1.2: 74 percent / 1,2-dimethoxy-ethane; hexane / 2.5 h / 0 °C
2.1: 92 percent / KOH / ethanol / 20 h / Heating
3.1: SOCl2 / 1 h / Heating
4.1: 1.51 g / sodium azide; tetrabutylammonium bromide / CH2Cl2; H2O / 2 h / 0 °C
With
potassium hydroxide; n-butyllithium; thionyl chloride; sodium azide; tetrabutylammomium bromide;
In
1,2-dimethoxyethane; ethanol; hexane; dichloromethane; water;
DOI:10.1021/jo034452g
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 81 percent / sodium ethoxide / ethanol / 3 h / Heating
2.1: 51 percent / DIBALH / CH2Cl2; toluene / 3 h / -78 °C
3.1: BuLi / 1,2-dimethoxy-ethane; hexane / 1 h / 0 °C
3.2: 74 percent / 1,2-dimethoxy-ethane; hexane / 2.5 h / 0 °C
4.1: 92 percent / KOH / ethanol / 20 h / Heating
5.1: SOCl2 / 1 h / Heating
6.1: 1.51 g / sodium azide; tetrabutylammonium bromide / CH2Cl2; H2O / 2 h / 0 °C
With
potassium hydroxide; n-butyllithium; thionyl chloride; sodium azide; tetrabutylammomium bromide; sodium ethanolate; diisobutylaluminium hydride;
In
1,2-dimethoxyethane; ethanol; hexane; dichloromethane; water; toluene;
DOI:10.1021/jo034452g
