5-(2-morpholin-4-yl-ethoxy)-2-(4-nitrophenyl)imidazo[2,1-b][1,3]benzothiazole

Base Information

Chemical Name:5-(2-morpholin-4-yl-ethoxy)-2-(4-nitrophenyl)imidazo[2,1-b][1,3]benzothiazole
CAS No.:1191251-68-9
Molecular Formula:C₂₁H₂₀N₄O₄S
Molecular Weight:424.48
Hs Code.:

Synonyms:5-(2-morpholin-4-yl-ethoxy)-2-(4-nitrophenyl)imidazo[2,1-b][1,3]benzothiazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(2-morpholin-4-yl-ethoxy)-2-(4-nitrophenyl)imidazo[2,1-b][1,3]benzothiazole

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Technology Process of 5-(2-morpholin-4-yl-ethoxy)-2-(4-nitrophenyl)imidazo[2,1-b][1,3]benzothiazole

There total 1 articles about 5-(2-morpholin-4-yl-ethoxy)-2-(4-nitrophenyl)imidazo[2,1-b][1,3]benzothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1191251-66-7
2-(4-nitrophenyl)imidazo[2,1-b][1,3]benzothiazol-5-ol

: 3647-69-6
4-(2-chloroethyl)morpholine hydrochride

: 1191251-68-9
5-(2-morpholin-4-yl-ethoxy)-2-(4-nitrophenyl)imidazo[2,1-b][1,3]benzothiazole

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 60 - 70 ℃; for 18h; Inert atmosphere;
DOI:10.1021/jm9007533

Reference yield: 96.0%

: 1191251-68-9
5-(2-morpholin-4-yl-ethoxy)-2-(4-nitrophenyl)imidazo[2,1-b][1,3]benzothiazole

: 1191251-71-4
2-(4-aminophenyl)-5-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazole

Guidance literature:: 5-(2-morpholin-4-yl-ethoxy)-2-(4-nitrophenyl)imidazo[2,1-b][1,3]benzothiazole; With ammonium chloride; In ethanol; Inert atmosphere; Reflux;

With iron; In ethanol; for 3h; Inert atmosphere; Reflux;
DOI:10.1021/jm9007533