N-tert-butoxycarbonyl-2-(4-chlorophenyl)-2-(2-chloro-4-amino-5-methylphenyl)ethylamine

Base Information

Chemical Name:N-tert-butoxycarbonyl-2-(4-chlorophenyl)-2-(2-chloro-4-amino-5-methylphenyl)ethylamine
CAS No.:212135-76-7
Molecular Formula:C₂₀H₂₄Cl₂N₂O₂
Molecular Weight:395.329
Hs Code.:

Synonyms:N-tert-butoxycarbonyl-2-(4-chlorophenyl)-2-(2-chloro-4-amino-5-methylphenyl)ethylamine

Suppliers and Price of N-tert-butoxycarbonyl-2-(4-chlorophenyl)-2-(2-chloro-4-amino-5-methylphenyl)ethylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-tert-butoxycarbonyl-2-(4-chlorophenyl)-2-(2-chloro-4-amino-5-methylphenyl)ethylamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-tert-butoxycarbonyl-2-(4-chlorophenyl)-2-(2-chloro-4-amino-5-methylphenyl)ethylamine

There total 3 articles about N-tert-butoxycarbonyl-2-(4-chlorophenyl)-2-(2-chloro-4-amino-5-methylphenyl)ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 4-[2-Amino-1-(4-chloro-phenyl)-ethyl]-5-chloro-2-methyl-phenylamine; hydrochloride

: 212135-76-7
N-tert-butoxycarbonyl-2-(4-chlorophenyl)-2-(2-chloro-4-amino-5-methylphenyl)ethylamine

Guidance literature:: With triethylamine; In tetrahydrofuran; at 5 ℃; for 16h;
DOI:10.1021/jm9803572

Reference yield:

: 61437-85-2
2-(4-amino-2-chloro-5-methylphenyl)-2-(4-chlorophenyl)acetonitrile

: 212135-76-7
N-tert-butoxycarbonyl-2-(4-chlorophenyl)-2-(2-chloro-4-amino-5-methylphenyl)ethylamine

Guidance literature:: Multi-step reaction with 3 steps

1: 66 percent / H₂, AcOH / Raney Ni / 21 h / 2585.7 Torr

2: 65 percent / conc. HCl / ethanol / 24 h / Heating

3: 95 percent / Et₃N / tetrahydrofuran / 16 h / 5 °C

With hydrogenchloride; hydrogen; acetic acid; triethylamine; nickel; In tetrahydrofuran; ethanol;
DOI:10.1021/jm9803572

Reference yield:

: N-[2-(4-chlorophenyl)-2-(2-chloro-4-acetylamino-5-methylphenyl)]ethylacetamide

: 212135-76-7
N-tert-butoxycarbonyl-2-(4-chlorophenyl)-2-(2-chloro-4-amino-5-methylphenyl)ethylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / conc. HCl / ethanol / 24 h / Heating

2: 95 percent / Et₃N / tetrahydrofuran / 16 h / 5 °C

With hydrogenchloride; triethylamine; In tetrahydrofuran; ethanol;
DOI:10.1021/jm9803572