2'-Deoxy-3,7-dideazaadenosine

Base Information

Chemical Name:2'-Deoxy-3,7-dideazaadenosine
CAS No.:114915-06-9
Molecular Formula:C₁₂H₁₅N₃O₃
Molecular Weight:249.269
Hs Code.:
DSSTox Substance ID:DTXSID70150900
Wikidata:Q83017208
Mol file:114915-06-9.mol

Synonyms:2'-deoxy-3,7-dideazaadenosine;2-DDAD

Suppliers and Price of 2'-Deoxy-3,7-dideazaadenosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2'-Deoxy-3,7-dideazaadenosine

Chemical Property:

Boiling Point:593.3°Cat760mmHg
Flash Point:312.6°C
PSA：94.26000
Density:1.62g/cm³
LogP:0.18930
XLogP3:-0.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:249.11134135
Heavy Atom Count:18
Complexity:304

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(OC1N2C=CC3=C2C=CN=C3N)CO)O
Isomeric SMILES:C1[C@@H]([C@H](O[C@@H]1N2C=CC3=C2C=CN=C3N)CO)O

Technology Process of 2'-Deoxy-3,7-dideazaadenosine

There total 7 articles about 2'-Deoxy-3,7-dideazaadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 114915-05-8
4-Amino-6-chloro-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1H-pyrrolo<3,2-c>pyridine

: 114915-06-9
4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)pyrrolo<3,2-c>pyridine

Guidance literature:: With ammonia; hydrogen; palladium on activated charcoal; In methanol; for 30h; Ambient temperature;
DOI:10.1055/s-1988-27759

Reference yield:

: 91713-48-3
4,6-Dichloro-1-<2-deoxy-3,5-bis-O-(4-methylbenzoyl)-β-D-erythro-pentofuranosyl>-1H-pyrrolo<3,2-c>pyridine

: 114915-06-9
4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)pyrrolo<3,2-c>pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / NH₃ / methanol / 24 h / Ambient temperature

2: 1) N₂H₄*H₂O, 2) Raney nickel / 1) reflux, 1.5 h, 2) water, reflux, 45 min

With ammonia; nickel; hydrazine hydrate; In methanol;
DOI:10.1021/jm00127a011

Reference yield:

: 4330-21-6
2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride

: 114915-06-9
4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)pyrrolo<3,2-c>pyridine

Guidance literature:: Multi-step reaction with 5 steps

1: 90 percent / KOH, cryptand TDA-1 / acetonitrile / 0.75 h / Ambient temperature

2: 72 percent / NH₃ / methanol / 12 h / 50 °C

3: N₂H₄ / 1 h / 80 °C

4: Raney nickel / ethanol / 2 h / Heating

5: 40 percent / NH₃, H₂ / 10percent Pd/C / methanol / 30 h / Ambient temperature

With potassium hydroxide; cryptand TDA-1; ammonia; hydrogen; nickel; hydrazine; palladium on activated charcoal; In methanol; ethanol; acetonitrile;
DOI:10.1055/s-1988-27759