4-O-(2-acetamido-4,6-di-O-allyl-3-O-benzyl-2-deoxy-α-D-glucopyranosyl)-6-O-p-anisyldiphenylmethyl-2,3-O-isopropylidene-aldehydo-L-idose dimethyl acetal

Base Information

Chemical Name:4-O-(2-acetamido-4,6-di-O-allyl-3-O-benzyl-2-deoxy-α-D-glucopyranosyl)-6-O-p-anisyldiphenylmethyl-2,3-O-isopropylidene-aldehydo-L-idose dimethyl acetal
CAS No.:131070-27-4
Molecular Formula:C₅₂H₆₅NO₁₃
Molecular Weight:912.087
Hs Code.:

4-O-(2-acetamido-4,6-di-O-allyl-3-O-benzyl-2-deoxy-α-D-glucopyranosyl)-6-O-p-anisyldiphenylmethyl-2,3-O-isopropylidene-aldehydo-L-idose dimethyl acetal

Synonyms:4-O-(2-acetamido-4,6-di-O-allyl-3-O-benzyl-2-deoxy-α-D-glucopyranosyl)-6-O-p-anisyldiphenylmethyl-2,3-O-isopropylidene-aldehydo-L-idose dimethyl acetal

Suppliers and Price of 4-O-(2-acetamido-4,6-di-O-allyl-3-O-benzyl-2-deoxy-α-D-glucopyranosyl)-6-O-p-anisyldiphenylmethyl-2,3-O-isopropylidene-aldehydo-L-idose dimethyl acetal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-O-(2-acetamido-4,6-di-O-allyl-3-O-benzyl-2-deoxy-α-D-glucopyranosyl)-6-O-p-anisyldiphenylmethyl-2,3-O-isopropylidene-aldehydo-L-idose dimethyl acetal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-O-(2-acetamido-4,6-di-O-allyl-3-O-benzyl-2-deoxy-α-D-glucopyranosyl)-6-O-p-anisyldiphenylmethyl-2,3-O-isopropylidene-aldehydo-L-idose dimethyl acetal

There total 14 articles about 4-O-(2-acetamido-4,6-di-O-allyl-3-O-benzyl-2-deoxy-α-D-glucopyranosyl)-6-O-p-anisyldiphenylmethyl-2,3-O-isopropylidene-aldehydo-L-idose dimethyl acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 131070-22-9,131070-26-3
4-O-(2-acetamido-4,6-di-O-allyl-3-O-benzyl-2-deoxy-α-D-glucopyranosyl)-2,3-O-isopropylidene-aldehydo-L-idose dimethyl acetal

: 14470-28-1
mono-4-methoxytrityl chloride

: 131070-27-4
4-O-(2-acetamido-4,6-di-O-allyl-3-O-benzyl-2-deoxy-α-D-glucopyranosyl)-6-O-p-anisyldiphenylmethyl-2,3-O-isopropylidene-aldehydo-L-idose dimethyl acetal

Guidance literature:: With pyridine; 2,2'-dimethylaminopyridine; In dichloromethane; for 8h;
DOI:10.1016/0008-6215(90)80149-W

Reference yield:

: 72200-55-6
2,3:5,6-Di-O-isopropylidene-4-O-(4',6'-O-isopropylidene-α-D-glucopyranosyl)-aldehydo-D-glucose dimethyl acetal

: 131070-27-4
4-O-(2-acetamido-4,6-di-O-allyl-3-O-benzyl-2-deoxy-α-D-glucopyranosyl)-6-O-p-anisyldiphenylmethyl-2,3-O-isopropylidene-aldehydo-L-idose dimethyl acetal

Guidance literature:: Multi-step reaction with 13 steps

1: 80 percent / imidazole / dimethylformamide / 5 h / 0 deg C --> room temperature

2: 68 percent / pyridinium chlorochromate, potassium acetate / benzene / 2 h / Heating

3: 97 percent / hydroxylamine hydrochloride, sodium acetate / methanol; H₂O; acetic acid / 4 h

4: lithium aluminium hydride / tetrahydrofuran

5: 86 percent / methanol / 2 h

6: 1.) sodium hydride, 2.) tetrabutylammonium bromide / 1.) tetrahydrofuran, 0 deg C, 10 min, 2.) 12 h

7: 73 percent / pyridinium p-toluenesulfonate / methanol / 8 h

8: 1.) sodium hydride / 1.) tetrahydrofuran, 10 min, 2.) 18 h, 60 deg C

9: 68 percent / aq. 80 percent acetic acid / 5 h / 40 °C

10: 74 percent / pyridine / CH₂Cl₂ / 3 h

11: potassium acetate / 20 h / 120 °C

12: sodium methoxide / methanol

13: 95 percent / 2,2'-dimethylaminopyridine, pyridine / CH₂Cl₂ / 8 h

With pyridine; 1H-imidazole; lithium aluminium tetrahydride; 2,2'-dimethylaminopyridine; hydroxylamine hydrochloride; tetrabutylammomium bromide; sodium methylate; potassium acetate; sodium acetate; pyridinium p-toluenesulfonate; sodium hydride; acetic acid; pyridinium chlorochromate; In tetrahydrofuran; methanol; dichloromethane; water; acetic acid; N,N-dimethyl-formamide; benzene;
DOI:10.1016/0008-6215(90)80149-W

Reference yield:

: 131070-11-6
4-O-(3-O-tert-butyldimethylsilyl-4,6-O-isopropylidene-α-D-glucopyranosyl)-2,3;5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal

: 131070-27-4
4-O-(2-acetamido-4,6-di-O-allyl-3-O-benzyl-2-deoxy-α-D-glucopyranosyl)-6-O-p-anisyldiphenylmethyl-2,3-O-isopropylidene-aldehydo-L-idose dimethyl acetal

Guidance literature:: Multi-step reaction with 12 steps

1: 68 percent / pyridinium chlorochromate, potassium acetate / benzene / 2 h / Heating

2: 97 percent / hydroxylamine hydrochloride, sodium acetate / methanol; H₂O; acetic acid / 4 h

3: lithium aluminium hydride / tetrahydrofuran

4: 86 percent / methanol / 2 h

5: 1.) sodium hydride, 2.) tetrabutylammonium bromide / 1.) tetrahydrofuran, 0 deg C, 10 min, 2.) 12 h

6: 73 percent / pyridinium p-toluenesulfonate / methanol / 8 h

7: 1.) sodium hydride / 1.) tetrahydrofuran, 10 min, 2.) 18 h, 60 deg C

8: 68 percent / aq. 80 percent acetic acid / 5 h / 40 °C

9: 74 percent / pyridine / CH₂Cl₂ / 3 h

10: potassium acetate / 20 h / 120 °C

11: sodium methoxide / methanol

12: 95 percent / 2,2'-dimethylaminopyridine, pyridine / CH₂Cl₂ / 8 h

With pyridine; lithium aluminium tetrahydride; 2,2'-dimethylaminopyridine; hydroxylamine hydrochloride; tetrabutylammomium bromide; sodium methylate; potassium acetate; sodium acetate; pyridinium p-toluenesulfonate; sodium hydride; acetic acid; pyridinium chlorochromate; In tetrahydrofuran; methanol; dichloromethane; water; acetic acid; benzene;
DOI:10.1016/0008-6215(90)80149-W