[4-(3,4-dimethoxyphenyl)-4-(R)-(2,2,2-trifluoroacetylamino)butyl]carbamic acid benzyl ester

Base Information

Chemical Name:[4-(3,4-dimethoxyphenyl)-4-(R)-(2,2,2-trifluoroacetylamino)butyl]carbamic acid benzyl ester
CAS No.:944256-10-4
Molecular Formula:C₂₂H₂₅F₃N₂O₅
Molecular Weight:454.446
Hs Code.:

Synonyms:[4-(3,4-dimethoxyphenyl)-4-(R)-(2,2,2-trifluoroacetylamino)butyl]carbamic acid benzyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of [4-(3,4-dimethoxyphenyl)-4-(R)-(2,2,2-trifluoroacetylamino)butyl]carbamic acid benzyl ester

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Technology Process of [4-(3,4-dimethoxyphenyl)-4-(R)-(2,2,2-trifluoroacetylamino)butyl]carbamic acid benzyl ester

There total 1 articles about [4-(3,4-dimethoxyphenyl)-4-(R)-(2,2,2-trifluoroacetylamino)butyl]carbamic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 944256-09-1
[4-(R)-amino-4-(3,4-dimethoxyphenyl)butyl]carbamic acid benzyl ester

: 407-25-0
trifluoroacetic anhydride

: 944256-10-4
[4-(3,4-dimethoxyphenyl)-4-(R)-(2,2,2-trifluoroacetylamino)butyl]carbamic acid benzyl ester

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃; for 3h;

Reference yield: 90.0%

: 944256-10-4
[4-(3,4-dimethoxyphenyl)-4-(R)-(2,2,2-trifluoroacetylamino)butyl]carbamic acid benzyl ester

: 944256-11-5
N-[4-amino-1-(R)-(3,4-dimethoxyphenyl)butyl]-2,2,2-trifluoroacetamide

Guidance literature:: With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In ethanol; water; ethyl acetate; for 24h; under 3345.86 Torr;
DOI:10.1021/jm900683d

Reference yield: 90.0%

: 944256-10-4
[4-(3,4-dimethoxyphenyl)-4-(R)-(2,2,2-trifluoroacetylamino)butyl]carbamic acid benzyl ester

: 1093069-74-9
C₁₄H₁₉F₃N₂O₃*ClH

Guidance literature:: With hydrogenchloride; hydrogen; palladium 10% on activated carbon; In ethanol; water; ethyl acetate; for 24h; under 2585.81 Torr;