N-isopropyl-2-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yloxy)-N-(4-(trifluoromethyl)phenyl)acetamide

Base Information

Chemical Name:N-isopropyl-2-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yloxy)-N-(4-(trifluoromethyl)phenyl)acetamide
CAS No.:1374298-95-9
Molecular Formula:C₁₅H₁₃F₆N₃O₂S
Molecular Weight:413.344
Hs Code.:

Synonyms:N-isopropyl-2-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yloxy)-N-(4-(trifluoromethyl)phenyl)acetamide

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Chemical Property of N-isopropyl-2-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yloxy)-N-(4-(trifluoromethyl)phenyl)acetamide

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Technology Process of N-isopropyl-2-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yloxy)-N-(4-(trifluoromethyl)phenyl)acetamide

There total 2 articles about N-isopropyl-2-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yloxy)-N-(4-(trifluoromethyl)phenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.9%

: 27603-25-4
2-(methylsulfonyl)-5-(trifluoromethyl)-1,3,4-thiadiazole

: C₁₂H₁₄F₃NO₂

: 1374298-95-9
N-isopropyl-2-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yloxy)-N-(4-(trifluoromethyl)phenyl)acetamide

Guidance literature:: With tetraethylammonium bromide; potassium carbonate; In acetone; at 20 ℃; for 20h;
DOI:10.14233/ajchem.2013.15239

Reference yield:

: C₁₂H₁₃ClF₃NO

: 1374298-95-9
N-isopropyl-2-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yloxy)-N-(4-(trifluoromethyl)phenyl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: potassium acetate; methanol

2: tetraethylammonium bromide; potassium carbonate / acetone / 20 h / 20 °C

With methanol; tetraethylammonium bromide; potassium acetate; potassium carbonate; In acetone;
DOI:10.14233/ajchem.2013.15239