4-(4-Nitrophenyl)-1,3-thiazol-2(3H)-one

Base Information

Chemical Name:4-(4-Nitrophenyl)-1,3-thiazol-2(3H)-one
CAS No.:2104-08-7
Molecular Formula:C₉H₆N₂O₃S
Molecular Weight:222.224
Hs Code.:
DSSTox Substance ID:DTXSID10508683
Nikkaji Number:J1.721.649J
Wikidata:Q82365809
Mol file:2104-08-7.mol

Synonyms:2104-08-7;SCHEMBL11491739;SCHEMBL16414817;DTXSID10508683;AKOS009428036;4-(4-Nitrophenyl)-1,3-thiazol-2(3H)-one

Suppliers and Price of 4-(4-Nitrophenyl)-1,3-thiazol-2(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-(4-NITROPHENYL)-2-(3H)-THIAZOLONE 95.00%
5MG
$ 496.09

Total 4 raw suppliers

Chemical Property of 4-(4-Nitrophenyl)-1,3-thiazol-2(3H)-one

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:222.00991323
Heavy Atom Count:15
Complexity:316

Purity/Quality:

99% ^*data from raw suppliers

4-(4-NITROPHENYL)-2-(3H)-THIAZOLONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CSC(=O)N2)[N+](=O)[O-]

Technology Process of 4-(4-Nitrophenyl)-1,3-thiazol-2(3H)-one

There total 4 articles about 4-(4-Nitrophenyl)-1,3-thiazol-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6097-21-8
2-(4-nitrophenyl)-2-oxoethyl thiocyanate

: 2104-08-7
4-(4-nitrophenyl)-2-oxo-thiazole

Guidance literature:: With sulfuric acid; In acetic acid; for 0.166667h; Heating;
DOI:10.1039/b106322g

Reference yield:

: 99-81-0
4-Nitrophenacyl bromide

: 2104-08-7
4-(4-nitrophenyl)-2-oxo-thiazole

Guidance literature:: Multi-step reaction with 2 steps

1: acetone / 0.5 h / 20 °C / Inert atmosphere

2: sulfuric acid; acetic acid / 1 h / 100 °C / Inert atmosphere

With sulfuric acid; acetic acid; In acetone;
DOI:10.1021/jm301793a

Reference yield:

: 100-19-6
(4-nitrophenyl)ethanone

: 2104-08-7
4-(4-nitrophenyl)-2-oxo-thiazole

Guidance literature:: Multi-step reaction with 3 steps

1: copper(ll) bromide / ethyl acetate / Reflux; Inert atmosphere

2: acetone / 0.5 h / 20 °C / Inert atmosphere

3: sulfuric acid; acetic acid / 1 h / 100 °C / Inert atmosphere

With sulfuric acid; acetic acid; copper(ll) bromide; In ethyl acetate; acetone;
DOI:10.1021/jm301793a