C₂₆H₃₈N₂O₅

Base Information

• Chemical Name: C₂₆H₃₈N₂O₅
• CAS No.: 1017279-87-6
• Molecular Formula: C₂₆H₃₈N₂O₅
• Molecular Weight: 458.598
• Mol file: 1017279-87-6.mol

Synonyms:C₂₆H₃₈N₂O₅

Chemical Property of C₂₆H₃₈N₂O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₂₆H₃₈N₂O₅

There total 1 articles about C₂₆H₃₈N₂O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

tert-butyl (1S,3R)-3-amino-2,2-dimethylcyclobutane-1-carboxylate (1017279-85-4) + (1S,3R)-3-(((benzyloxy)carbonyl)amino)-2,2-dimethylcyclobutanecarboxylic acid (1017279-82-1) → C26H38N2O5 (1017279-87-6)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 168h;

DOI:10.1016/j.tetasy.2008.01.020

Reference yield: 96.0%

C26H38N2O5 (1017279-87-6) → C22H30N2O5

Guidance literature:

With triethylsilane; trifluoroacetic acid; In dichloromethane; at 20 ℃; for 18h;

DOI:10.1002/ejoc.201300066

Reference yield:

C26H38N2O5 (1017279-87-6) → C40H60N4O7

Guidance literature:

Multi-step reaction with 2 steps

1.1: hydrogen; palladium 10% on activated carbon / methanol / 1520.1 Torr

2.1: triethylamine; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / N,N-dimethyl-formamide / 0.33 h / Inert atmosphere

2.2: 15 h / 20 °C

With palladium 10% on activated carbon; hydrogen; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; In methanol; N,N-dimethyl-formamide;

DOI:10.1002/ejoc.201300066

upstream raw materials:

tert-butyl (1S,3R)-3-amino-2,2-dimethylcyclobutane-1-carboxylate

(1S,3R)-3-(((benzyloxy)carbonyl)amino)-2,2-dimethylcyclobutanecarboxylic acid