N-p-chlorophenyl-α-p-chlorophenylstyrylacrylohydroxamic acid

Base Information

• Chemical Name: N-p-chlorophenyl-α-p-chlorophenylstyrylacrylohydroxamic acid
• CAS No.: 163188-54-3
• Molecular Formula: C₂₃H₁₇Cl₂NO₂
• Molecular Weight: 410.299
• Mol file: 163188-54-3.mol

Synonyms:N-p-chlorophenyl-α-p-chlorophenylstyrylacrylohydroxamic acid

Chemical Property of N-p-chlorophenyl-α-p-chlorophenylstyrylacrylohydroxamic acid

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of N-p-chlorophenyl-α-p-chlorophenylstyrylacrylohydroxamic acid

There total 2 articles about N-p-chlorophenyl-α-p-chlorophenylstyrylacrylohydroxamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

2-(4-chloro-phenyl)-5-phenyl-penta-2,4-dienoyl chloride + N-(4-chlorophenyl)hydroxylamine (823-86-9) → N-p-chlorophenyl-α-p-chlorophenylstyrylacrylohydroxamic acid (163188-54-3)

Guidance literature:

With sodium hydrogencarbonate; In diethyl ether; water; at 0 ℃; for 0.25h;

DOI:10.1021/je00018a013

Reference yield:

2-(4-chloro-phenyl)-5-phenyl-penta-2,4-dienoic acid (163188-46-3) → N-p-chlorophenyl-α-p-chlorophenylstyrylacrylohydroxamic acid (163188-54-3)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂ / 5 h / Heating

2: 76 percent / NaHCO₃ / diethyl ether; H₂O / 0.25 h / 0 °C

With thionyl chloride; sodium hydrogencarbonate; In diethyl ether; water;

DOI:10.1021/je00018a013

Reference yield:

N-p-chlorophenyl-α-p-chlorophenylstyrylacrylohydroxamic acid (163188-54-3) → 2-(4-chloro-phenyl)-5-phenyl-penta-2,4-dienoic acid (163188-46-3) + N-(4-chlorophenyl)hydroxylamine (823-86-9)

Guidance literature:

With sodium hydroxide; In methanol; at 35 ℃; for 48h; Mechanism; Rate constant;

DOI:10.1021/je00018a013

upstream raw materials:

N-(4-chlorophenyl)hydroxylamine

2-(4-chloro-phenyl)-5-phenyl-penta-2,4-dienoic acid

Downstream raw materials:

2-(4-chloro-phenyl)-5-phenyl-penta-2,4-dienoic acid

N-(4-chlorophenyl)hydroxylamine