phosphoric acid di-tert-butyl ester (R)-3-{3-fluoro-4-[6-((S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yloxy)-pyridin-3-yl]-phenyl}-2-oxo-oxazolidin-5-ylmethyl ester

Base Information

Chemical Name:phosphoric acid di-tert-butyl ester (R)-3-{3-fluoro-4-[6-((S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yloxy)-pyridin-3-yl]-phenyl}-2-oxo-oxazolidin-5-ylmethyl ester
CAS No.:1188337-57-6
Molecular Formula:C₂₉H₃₅FN₅O₁₀P
Molecular Weight:663.597
Hs Code.:

phosphoric acid di-tert-butyl ester (R)-3-{3-fluoro-4-[6-((S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yloxy)-pyridin-3-yl]-phenyl}-2-oxo-oxazolidin-5-ylmethyl ester

Synonyms:phosphoric acid di-tert-butyl ester (R)-3-{3-fluoro-4-[6-((S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yloxy)-pyridin-3-yl]-phenyl}-2-oxo-oxazolidin-5-ylmethyl ester

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Chemical Property of phosphoric acid di-tert-butyl ester (R)-3-{3-fluoro-4-[6-((S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yloxy)-pyridin-3-yl]-phenyl}-2-oxo-oxazolidin-5-ylmethyl ester

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Technology Process of phosphoric acid di-tert-butyl ester (R)-3-{3-fluoro-4-[6-((S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yloxy)-pyridin-3-yl]-phenyl}-2-oxo-oxazolidin-5-ylmethyl ester

There total 1 articles about phosphoric acid di-tert-butyl ester (R)-3-{3-fluoro-4-[6-((S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yloxy)-pyridin-3-yl]-phenyl}-2-oxo-oxazolidin-5-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1188405-34-6
(R)‐3‐(3‐fluoro‐4‐(6‐(((S)‐2‐nitro‐6,7‐dihydro‐5H‐imidazo[2,1‐b][1,3]oxazin‐6‐yl)oxy)pyridin‐3‐yl)phenyl)‐5‐(hydroxymethyl)oxazolidin‐2‐one

: 137348-86-8
di-tert-butyl diisopropylphosphoramide

: 1188337-57-6
phosphoric acid di-tert-butyl ester (R)-3-{3-fluoro-4-[6-((S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yloxy)-pyridin-3-yl]-phenyl}-2-oxo-oxazolidin-5-ylmethyl ester

Guidance literature:: (R)‐3‐(3‐fluoro‐4‐(6‐(((S)‐2‐nitro‐6,7‐dihydro‐5H‐imidazo[2,1‐b][1,3]oxazin‐6‐yl)oxy)pyridin‐3‐yl)phenyl)‐5‐(hydroxymethyl)oxazolidin‐2‐one; di-tert-butyl diisopropylphosphoramide; With 1H-tetrazole; In tetrahydrofuran; dichloromethane; acetonitrile; at 20 ℃; for 16h;

With 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; acetonitrile; at -78 - 20 ℃;