Technology Process of N-[(1S,2R,3S,6S)-2,3-dibenzyloxy-6-hydroxy-4-oxocyclohexyl]acetamide
There total 6 articles about N-[(1S,2R,3S,6S)-2,3-dibenzyloxy-6-hydroxy-4-oxocyclohexyl]acetamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium iodide / N,N-dimethyl-formamide / 3 h / 80 °C
1.2: 3 h / 20 °C
2.1: sulfuric acid; mercury(II) sulfate / 1,4-dioxane / 3 h / 50 °C
With
sulfuric acid; mercury(II) sulfate; sodium iodide;
In
1,4-dioxane; N,N-dimethyl-formamide;
2.1: |Ferrier Carbohydrate Rearrangement;
DOI:10.1016/j.tet.2018.02.063
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: hydrogen bromide / dichloromethane; acetic acid / 0.17 h / 0 °C
2.1: dmap; triethylamine / dichloromethane / 13 h / 0 - 20 °C
3.1: sodium iodide / N,N-dimethyl-formamide / 3 h / 80 °C
3.2: 3 h / 20 °C
4.1: sulfuric acid; mercury(II) sulfate / 1,4-dioxane / 3 h / 50 °C
With
dmap; sulfuric acid; hydrogen bromide; mercury(II) sulfate; triethylamine; sodium iodide;
In
1,4-dioxane; dichloromethane; acetic acid; N,N-dimethyl-formamide;
4.1: |Ferrier Carbohydrate Rearrangement;
DOI:10.1016/j.tet.2018.02.063