potassium 2-(4-chlorophenyl)-3-((2,2,2-trifluoroethyl)amino)propanoate

Base Information

Chemical Name:potassium 2-(4-chlorophenyl)-3-((2,2,2-trifluoroethyl)amino)propanoate
CAS No.:1001180-67-1
Molecular Formula:C₁₁H₁₀ClF₃NO₂*K
Molecular Weight:319.752
Hs Code.:

Synonyms:potassium 2-(4-chlorophenyl)-3-((2,2,2-trifluoroethyl)amino)propanoate

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Chemical Property of potassium 2-(4-chlorophenyl)-3-((2,2,2-trifluoroethyl)amino)propanoate

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Technology Process of potassium 2-(4-chlorophenyl)-3-((2,2,2-trifluoroethyl)amino)propanoate

There total 7 articles about potassium 2-(4-chlorophenyl)-3-((2,2,2-trifluoroethyl)amino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1001180-65-9
methyl 2-(4-chlorophenyl)-3-((2,2,2-trifluoroethyl)amino)propanoate

: 10519-96-7
potassium trimethylsilonate

: 1001180-67-1
potassium 2-(4-chlorophenyl)-3-((2,2,2-trifluoroethyl)amino)propanoate

Guidance literature:: In tetrahydrofuran; at 20 ℃; for 18h;

Reference yield: 100.0%

: 1001180-65-9
methyl 2-(4-chlorophenyl)-3-((2,2,2-trifluoroethyl)amino)propanoate

: 1001180-67-1
potassium 2-(4-chlorophenyl)-3-((2,2,2-trifluoroethyl)amino)propanoate

Guidance literature:: With potassium trimethylsilonate; In tetrahydrofuran; at 20 ℃; for 18h;
DOI:10.1021/jm301024w

Reference yield:

: 1001180-63-7
methyl 3-amino-2-(4-chlorophenyl)propanoate hydrochloride

: 1001180-67-1
potassium 2-(4-chlorophenyl)-3-((2,2,2-trifluoroethyl)amino)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran; N,N-dimethyl-formamide / 20 h / 20 °C

2: tetrahydrofuran / 18 h / 20 °C

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; N,N-dimethyl-formamide;