N^δ-{[(N-benzyloxycarbonylamino)-2,5-dihydro-1H-pyrrol-1-yl]methylidene}-N^α-tert-butyloxycarbonyl-L-ornithine tert-butyl ester

Base Information

• Chemical Name: N^δ-{[(N-benzyloxycarbonylamino)-2,5-dihydro-1H-pyrrol-1-yl]methylidene}-N^α-tert-butyloxycarbonyl-L-ornithine tert-butyl ester
• CAS No.: 1061262-11-0
• Molecular Formula: C₂₇H₄₀N₄O₆
• Molecular Weight: 516.638

Synonyms:N^δ-{[(N-benzyloxycarbonylamino)-2,5-dihydro-1H-pyrrol-1-yl]methylidene}-N^α-tert-butyloxycarbonyl-L-ornithine tert-butyl ester

Chemical Property of N^δ-{[(N-benzyloxycarbonylamino)-2,5-dihydro-1H-pyrrol-1-yl]methylidene}-N^α-tert-butyloxycarbonyl-L-ornithine tert-butyl ester

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Technology Process of N^δ-{[(N-benzyloxycarbonylamino)-2,5-dihydro-1H-pyrrol-1-yl]methylidene}-N^α-tert-butyloxycarbonyl-L-ornithine tert-butyl ester

There total 1 articles about N^δ-{[(N-benzyloxycarbonylamino)-2,5-dihydro-1H-pyrrol-1-yl]methylidene}-N^α-tert-butyloxycarbonyl-L-ornithine tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

3-Pyrroline (109-96-6,760178-50-5) + Nω-benzyloxycarbonyl-Nα-tert-butyloxycarbonyl-L-thiocitrulline tert-butyl ester (1061261-89-9) → Nδ-{[(N-benzyloxycarbonylamino)-2,5-dihydro-1H-pyrrol-1-yl]methylidene}-Nα-tert-butyloxycarbonyl-L-ornithine tert-butyl ester (1061262-11-0)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane;

DOI:10.1055/s-2008-1067165

upstream raw materials:

3-Pyrroline

N^ω-benzyloxycarbonyl-N^α-tert-butyloxycarbonyl-L-thiocitrulline tert-butyl ester

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