3-(4-trifluoromethylphenyl)propan-1-ol sulfamate ester

Base Information

• Chemical Name: 3-(4-trifluoromethylphenyl)propan-1-ol sulfamate ester
• CAS No.: 1042906-15-9
• Molecular Formula: C₁₀H₁₂F₃NO₃S
• Molecular Weight: 283.271
• Mol file: 1042906-15-9.mol

Synonyms:3-(4-trifluoromethylphenyl)propan-1-ol sulfamate ester

Chemical Property of 3-(4-trifluoromethylphenyl)propan-1-ol sulfamate ester

Chemical Property:

Purity/Quality:

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Technology Process of 3-(4-trifluoromethylphenyl)propan-1-ol sulfamate ester

There total 2 articles about 3-(4-trifluoromethylphenyl)propan-1-ol sulfamate ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

→ 3-(4-trifluoromethylphenyl)propan-1-ol sulfamate ester (1042906-15-9)

Guidance literature:

With formic acid; isocyanate de chlorosulfonyle; triethylamine; In dichloromethane; at 0 - 20 ℃;

Reference yield: 66.0%

3‐(4‐(trifluoromethyl)phenyl)propan‐1‐ol (180635-74-9) → 3-(4-trifluoromethylphenyl)propan-1-ol sulfamate ester (1042906-15-9)

Guidance literature:

With formic acid; isocyanate de chlorosulfonyle; triethylamine; In dichloromethane; at 0 - 25 ℃; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.9b00660

Reference yield: 71.0%

3-(4-trifluoromethylphenyl)propan-1-ol sulfamate ester (1042906-15-9) → (±)-4-(4-(trifluoromethyl)phenyl)-1,2,3-oxathiazinane 2,2-dioxide (1126527-72-7)

Guidance literature:

With sodium hypochlorite; disodium hydrogenphosphate; rhodium (II) octanoate dimer; sodium bromide; In dichloromethane; water; for 2h; pH=9;

DOI:10.1055/s-0028-1087392

upstream raw materials:

3‐(4‐(trifluoromethyl)phenyl)propan‐1‐ol

Downstream raw materials:

C₁₀H₁₀F₃NO₃S

(±)-4-(4-(trifluoromethyl)phenyl)-1,2,3-oxathiazinane 2,2-dioxide