alpha-(Aminomethyl)-4-hydroxy-3,5-dimethylbenzenemethanol

Base Information

Chemical Name:alpha-(Aminomethyl)-4-hydroxy-3,5-dimethylbenzenemethanol
CAS No.:325151-59-5
Molecular Formula:C₁₀H₁₅NO₂
Molecular Weight:181.235
Hs Code.:
DSSTox Substance ID:DTXSID601215404

Synonyms:SCHEMBL8310005;DTXSID601215404;AKOS000123921;325151-59-5;I+/--(Aminomethyl)-4-hydroxy-3,5-dimethylbenzenemethanol

Suppliers and Price of alpha-(Aminomethyl)-4-hydroxy-3,5-dimethylbenzenemethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of alpha-(Aminomethyl)-4-hydroxy-3,5-dimethylbenzenemethanol

Chemical Property:

XLogP3:0.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:181.110278721
Heavy Atom Count:13
Complexity:151

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=CC(=C1O)C)C(CN)O

Technology Process of alpha-(Aminomethyl)-4-hydroxy-3,5-dimethylbenzenemethanol

There total 2 articles about alpha-(Aminomethyl)-4-hydroxy-3,5-dimethylbenzenemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (4-hydroxy-3,5-dimethyl-phenyl)-trimethylsilanyloxy-acetonitrile

: 325151-59-5
4-(2-amino-1-hydroxy-ethyl)-2,6-dimethyl-phenol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at -30 - 0 ℃; for 1.5h;
DOI:10.1016/S0040-4020(00)00759-6

Reference yield:

: 2233-18-3
4-hydroxy-3,5-dimethylbenzaldehyde

: 325151-59-5
4-(2-amino-1-hydroxy-ethyl)-2,6-dimethyl-phenol

Guidance literature:: Multi-step reaction with 2 steps

1: 417 mg / ZnI₂ / 60 h / 20 °C

2: 91.2 mg / LiAlH₄ / tetrahydrofuran / 1.5 h / -30 - 0 °C

With lithium aluminium tetrahydride; zinc(II) iodide; In tetrahydrofuran; 1: Addition / 2: Reduction;
DOI:10.1016/S0040-4020(00)00759-6