(2S,3S)-1,4-bis(tert-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-2-butanol

Base Information

Chemical Name:(2S,3S)-1,4-bis(tert-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-2-butanol
CAS No.:156696-24-1
Molecular Formula:C₂₄H₄₆O₅Si₂
Molecular Weight:470.797
Hs Code.:

Synonyms:(2S,3S)-1,4-bis(tert-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-2-butanol

Suppliers and Price of (2S,3S)-1,4-bis(tert-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-2-butanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3S)-1,4-bis(tert-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-2-butanol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3S)-1,4-bis(tert-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-2-butanol

There total 4 articles about (2S,3S)-1,4-bis(tert-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-2-butanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 156696-23-0
(2S,3S)-1,4-bis(tert-butyldimethylsilyloxy)-2,3-O-(4-methoxybenzylidene)-2,3-butanediol

: 156696-24-1
(2S,3S)-1,4-bis(tert-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-2-butanol

Guidance literature:: With diisobutylaluminium hydride; In hexane; dichloromethane; at -78 - -30 ℃; for 1.5h;
DOI:10.1248/cpb.42.683

Reference yield:

: 2186-92-7
p-Anisaldehyde dimethyl acetal

: 156696-24-1
(2S,3S)-1,4-bis(tert-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-2-butanol

Guidance literature:: Multi-step reaction with 4 steps

1: 97 percent / molecular sieves, TsOH*H₂O / benzene / 16 h / Heating

2: 91 percent / LiAlH₄ / tetrahydrofuran / 1 h / Ambient temperature

3: 97 percent / imidazole / CH₂Cl₂ / 0.5 h / Ambient temperature

4: 81 percent / DIBAH / hexane; CH₂Cl₂ / 1.5 h / -78 - -30 °C

With 1H-imidazole; lithium aluminium tetrahydride; molecular sieve; diisobutylaluminium hydride; toluene-4-sulfonic acid; In tetrahydrofuran; hexane; dichloromethane; benzene;
DOI:10.1248/cpb.42.683

Reference yield:

: 130874-90-7
4,5-dimethyl (4R,5R)-2-(4-methoxyphenyl)-1,3-dioxolane-4,5-dicarboxylate

: 156696-24-1
(2S,3S)-1,4-bis(tert-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-2-butanol

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / LiAlH₄ / tetrahydrofuran / 1 h / Ambient temperature

2: 97 percent / imidazole / CH₂Cl₂ / 0.5 h / Ambient temperature

3: 81 percent / DIBAH / hexane; CH₂Cl₂ / 1.5 h / -78 - -30 °C

With 1H-imidazole; lithium aluminium tetrahydride; diisobutylaluminium hydride; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1248/cpb.42.683