Narcotine, (+)-

Base Information

Chemical Name:Narcotine, (+)-
CAS No.:35933-64-3
Molecular Formula:C₂₂H₂₃NO₇
Molecular Weight:413.427
Hs Code.:
NSC Number:96350
UNII:Z4241U523E
Nikkaji Number:J1.175.639E
Wikidata:Q27166501
ChEMBL ID:CHEMBL1618357

Synonyms:Narcotine, (+)-;D-alpha-Narcotine;(+)-alpha-Narcotine;UNII-Z4241U523E;Z4241U523E;Gnoscopine;dl-Narcotine;1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-((5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (R-(R*,S*))-;35933-64-3;.alpha.-Gnoscopine;NSC-96350;(+)-narcotine;6035-40-1;Narcotine, (.+-.)-;D-.ALPHA.-NARCOTINE;(.+-.)-.alpha.-Narcotine;CHEMBL1618357;(+)-.ALPHA.-NARCOTINE;CHEBI:94697;NSC96350;BRD-K66043364-001-01-4;Q27166501;WLN: T C566 DO FO KN EH&&TJ HO1 K1 J- DT56 BVO DHJ HO1 IO1;1(3H)-Isobenzofuranone,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, (R*,S*)-(.+-.)-

Suppliers and Price of Narcotine, (+)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of Narcotine, (+)-

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:413.14745207
Heavy Atom Count:30
Complexity:647

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1CCC2=CC3=C(C(=C2C1C4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3
Isomeric SMILES:CN1CCC2=CC3=C(C(=C2[C@H]1[C@H]4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3

Technology Process of Narcotine, (+)-

There total 55 articles about Narcotine, (+)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: (+/-)-α-3-(9-bromo-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-6,7-dimethoxy-1(3H)-isobenzofuranone

: 128-62-1,3860-46-6,6035-40-1,10421-76-8,35933-62-1,35933-63-2,35933-64-3,85280-20-2
(±)-α-noscapine

Guidance literature:: With hydrogen; triethylamine; for 30h;
DOI:10.1016/j.tet.2011.05.060

Reference yield: 46.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 36017-64-8
(+/-)-erythro-1-<1'-(4',5'-dimethoxyphthalidyl)>-8-methoxy-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinoline

: 128-62-1,3860-46-6,6035-40-1,10421-76-8,35933-62-1,35933-63-2,35933-64-3,85280-20-2
(±)-α-noscapine

Guidance literature:: With formic acid; In water; at 100 ℃; for 0.166667h;

Reference yield: 42.0%

: 30936-27-7
4-methoxy-6-methyl-7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium iodide

: 133932-07-7
6,7-dimethoxy-3-(trimethylsilyl)isobenzofuran-1(3H)-one

: 128-62-1,3860-46-6,6035-40-1,10421-76-8,35933-62-1,35933-63-2,35933-64-3,85280-20-2
(±)-α-noscapine

Guidance literature:: With potassium hydrogen difluoride; In N,N-dimethyl-formamide; at 20 ℃; for 24h; Inert atmosphere;
DOI:10.3987/COM-13-12843