ethyl 4-(2,4-bis(4-chlorobenzyloxy)phenyl)-2-hydroxy-4-oxobut-2-enoate

Base Information

• Chemical Name: ethyl 4-(2,4-bis(4-chlorobenzyloxy)phenyl)-2-hydroxy-4-oxobut-2-enoate
• CAS No.: 1610532-57-4
• Molecular Formula: C₂₆H₂₂Cl₂O₆
• Molecular Weight: 501.363

Synonyms:ethyl 4-(2,4-bis(4-chlorobenzyloxy)phenyl)-2-hydroxy-4-oxobut-2-enoate

Chemical Property of ethyl 4-(2,4-bis(4-chlorobenzyloxy)phenyl)-2-hydroxy-4-oxobut-2-enoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 4-(2,4-bis(4-chlorobenzyloxy)phenyl)-2-hydroxy-4-oxobut-2-enoate

There total 3 articles about ethyl 4-(2,4-bis(4-chlorobenzyloxy)phenyl)-2-hydroxy-4-oxobut-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-(2,4-bis(4-chlorobenzyloxy)phenyl)ethanone (821780-54-5) + oxalic acid diethyl ester (95-92-1) → ethyl 4-(2,4-bis(4-chlorobenzyloxy)phenyl)-2-hydroxy-4-oxobut-2-enoate (1610532-57-4)

Guidance literature:

With sodium ethanolate; In tetrahydrofuran; ethanol; for 8h; Reflux;

DOI:10.2174/1573406411309080013

Reference yield:

2',4'-dihydroxy-4-acetophenone (89-84-9) → ethyl 4-(2,4-bis(4-chlorobenzyloxy)phenyl)-2-hydroxy-4-oxobut-2-enoate (1610532-57-4)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 6 h / 50 °C

2: sodium ethanolate / ethanol; tetrahydrofuran / 8 h / Reflux

With sodium ethanolate; potassium carbonate; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide;

DOI:10.2174/1573406411309080013

Reference yield:

1-Chloro-4-(chloromethyl)benzene (104-83-6) → ethyl 4-(2,4-bis(4-chlorobenzyloxy)phenyl)-2-hydroxy-4-oxobut-2-enoate (1610532-57-4)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 6 h / 50 °C

2: sodium ethanolate / ethanol; tetrahydrofuran / 8 h / Reflux

With sodium ethanolate; potassium carbonate; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide;

DOI:10.2174/1573406411309080013

upstream raw materials:

2',4'-dihydroxy-4-acetophenone

1-Chloro-4-(chloromethyl)benzene

1-(2,4-bis(4-chlorobenzyloxy)phenyl)ethanone

oxalic acid diethyl ester

Downstream raw materials:

ethyl 3-(2,4-bis(4-chlorobenzyloxy)phenyl)-1-phenyl-1H-pyrazole-5-carboxylate

ethyl 5-(2,4-bis(4-chlorobenzyloxy)phenyl)-1-phenyl-1H-pyrazole-3-carboxylate

ethyl 3-(2,4-bis(4-chlorobenzyloxy)phenyl)-1-ethyl-1H-pyrazole-5-carboxylate

3-(2,4-bis(4-chlorobenzyloxy)phenyl)-1H-pyrazole-5-carboxylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1610532-57-4 ethyl 4-(2,4-bis(4-chlorobenzyloxy)phenyl)-2-hydroxy-4-oxobut-2-enoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send