α-benzylamino-β-(5,5-dioxodibenzothiophen-2-carbonyl)propionic acid

Base Information

• Chemical Name: α-benzylamino-β-(5,5-dioxodibenzothiophen-2-carbonyl)propionic acid
• CAS No.: 479480-26-7
• Molecular Formula: C₂₃H₁₉NO₅S
• Molecular Weight: 421.474
• Mol file: 479480-26-7.mol

Synonyms:α-benzylamino-β-(5,5-dioxodibenzothiophen-2-carbonyl)propionic acid

Chemical Property of α-benzylamino-β-(5,5-dioxodibenzothiophen-2-carbonyl)propionic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-benzylamino-β-(5,5-dioxodibenzothiophen-2-carbonyl)propionic acid

There total 1 articles about α-benzylamino-β-(5,5-dioxodibenzothiophen-2-carbonyl)propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

benzylamine (100-46-9) + 4-(5,5-dioxodibenzothiophen-2-yl)-4-oxo-2-butenoic acid → α-benzylamino-β-(5,5-dioxodibenzothiophen-2-carbonyl)propionic acid (479480-26-7)

Guidance literature:

In benzene; for 3h; Heating;

DOI:10.1515/znb-2002-0613

Reference yield: 83.0%

α-benzylamino-β-(5,5-dioxodibenzothiophen-2-carbonyl)propionic acid (479480-26-7) → 4-benzylamino-6-(5,5-dioxodibenzothiophen-2-yl)-2,3,4,5-tetrahydropyridazin-3-one (479480-27-8)

Guidance literature:

With hydrazine hydrate; In ethanol; for 6h; Heating;

DOI:10.1515/znb-2002-0613

Reference yield:

α-benzylamino-β-(5,5-dioxodibenzothiophen-2-carbonyl)propionic acid (479480-26-7) → 8-benzylamino-6-(5,5-dioxodibenzothiophen-2-yl)-1,2,3,4-tetrazolo[1,5-b]-7,8-dihydropyridazine

Guidance literature:

Multi-step reaction with 3 steps

1: 83 percent / N₂H₄*H₂O / ethanol / 6 h / Heating

2: 82 percent / POCl₃; PCl₅ / 4 h / Heating

3: NaN₃ / dimethylformamide / 6 h / Heating

With sodium azide; phosphorus pentachloride; hydrazine hydrate; trichlorophosphate; In ethanol; N,N-dimethyl-formamide;

DOI:10.1515/znb-2002-0613

upstream raw materials:

benzylamine

Downstream raw materials:

4-benzylamino-6-(5,5-dioxodibenzothiophen-2-yl)-2,3,4,5-tetrahydropyridazin-3-one

4-benzylamino-3-chloro-6-(5,5-dioxodibenzothiophen-2-yl)-4,5-dihydropyridazine

4-benzylamino-6-(5,5-dioxodibenzothiophen-2-yl)-4,5-dihydropyridazin-3(2H)-thione

4-benzylamino-6-(5,5-dioxodibenzothiophen-2-yl)-3-hydrazino-4,5-dihydropyridazine