(3R)-3aβ,5,5a,9bβ-Tetrahydro-3α,5aα,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)-dione

Base Information

Chemical Name:(3R)-3aβ,5,5a,9bβ-Tetrahydro-3α,5aα,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)-dione
CAS No.:1618-77-5
Molecular Formula:C₁₅H₁₈O₃
Molecular Weight:246.306
Hs Code.:
Mol file:1618-77-5.mol

Synonyms:6-Epi-11aH-Santonin (7CI);Eudesma-1,4-dien-12-oic acid, 6b-hydroxy-3-oxo-, g-lactone, (11R)- (8CI); Naphtho[1,2-b]furan-2,8(3H,4H)-dione,3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-, [3R-(3a,3ab,5aa,9bb)]-; (6b,11b)-Santonin; 6-Epi-b-santonin; 6-epi-b-Santonin; Santonin D; b-Episantonin

Suppliers and Price of (3R)-3aβ,5,5a,9bβ-Tetrahydro-3α,5aα,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of (3R)-3aβ,5,5a,9bβ-Tetrahydro-3α,5aα,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)-dione

Chemical Property:

PSA：43.37000
LogP:2.41960

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (3R)-3aβ,5,5a,9bβ-Tetrahydro-3α,5aα,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)-dione

There total 91 articles about (3R)-3aβ,5,5a,9bβ-Tetrahydro-3α,5aα,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7647-01-0,15364-23-5
hydrogenchloride

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 481-06-1,481-07-2,1618-77-5,1618-78-6,3650-48-4,21295-21-6,64912-47-6,64912-48-7,135270-27-8,135270-28-9
α-Santonin

: 438-50-6,13743-88-9,13743-89-0,13743-96-9,16963-59-0,21142-64-3,5951-46-2
(+/-)-α-Desmotroposantonin

: 481-06-1,481-07-2,1618-77-5,1618-78-6,3650-48-4,21295-21-6,64912-47-6,64912-48-7,135270-27-8,135270-28-9
(+/-)-Santonin-C

Guidance literature:

Reference yield:

: 102315-35-5
rac-11-methyl-3-oxo-eudesm-4-ene-12,13-dioic acid diethyl ester

: 481-06-1,481-07-2,1618-77-5,1618-78-6,3650-48-4,21295-21-6,64912-47-6,64912-48-7,135270-27-8,135270-28-9
(+/-)-Santonin-D

Guidance literature:: Multi-step reaction with 7 steps

1: aq.-ethanolic KOH

2: diethyl ether; bromine

3: aqueous sodium hydrogencarbonate solution

4: diethyl ether; bromine

5: 5-ethyl-2-methyl-pyridine

6: aqueous KOH-solution / Erwaermen der Reaktionsloesung mit wss. Salzsaeure

7: 2,4,6-trimethyl-pyridine

With 2,4,6-trimethyl-pyridine; 5-ethyl-2-methyl-pyridine; potassium hydroxide; diethyl ether; bromine; sodium hydrogencarbonate;